医院获得性肺炎药物防治策略  

Progress on the Study of Hospital-acquired Pneumonia

作　　者：李性天[1] 耿立坚[1] 周密妹[1] 

机构地区：[1]武汉科技大学附属医院临床药学室,湖北武汉430064

出　　处：《抗感染药学》2009年第1期5-8,共4页Anti-infection Pharmacy

摘　　要：回顾近年来有关医院获得性肺炎的诊疗指南、病原体流行病学分析和抗感染药物对其预防和治疗方面的进展。最常见的病原菌为金黄色葡萄球菌和铜绿假单胞菌;氯己啶等消毒剂口腔用药可预防呼吸机相关肺炎发生,但此类消毒剂以及抗生素均不能降低其死亡率;在各类抗感染药物中,美罗培南、亚胺培南等碳青霉烯类对医院获得性肺炎的治疗作用优越。The purpose is to investigate the progress in guidelines for the management of hospital-acquired pneumonia （HAP）, epidemiology of causative organisms and the preventive and therapeutic effect of anti-infective drug. The most common pathogens were staphylococcus aureus and pseudomonas aeruginosa. Oral application of antiseptics including chlorhexidine, etc. reduced the incidence of ventilator associated pneumonia, but neither antiseptic nor antibiotic oral decontamination reduced mortality. Carbapenems（including meropenem, imipenem） as first line treatment had a positive effect with the efficacy rate of HAP.

关 键 词：医院获得性肺炎 诊断 病原学 药物预防 药物治疗 

分 类 号：R978[医药卫生—药品]