超声心动图监测评价体外反搏对冠心病患者左室舒张功能的影响  

Effect of External Counterpulsation on Left Ventricular Diastolic Founction in Patients with Coronary Heart Disease Assessed by Ultrasound Cardiogram

作　　者：朱苏航[1] 贾连旺[2] 杜永远[2] 

机构地区：[1]浙江金华职业技术学院,金华321007 [2]浙江省金华市中心医院,金华321000

出　　处：《中国医疗器械信息》2009年第3期22-25,共4页China Medical Device Information

摘　　要：目的:应用超声心动图观察体外反搏对冠心病患者左室舒张功能的影响。方法:随机将70例冠心病心肌缺血患者分为两组,其中35例在常规药物基础上加用体外反搏治疗为反搏组,另35例应用常规药物治疗为常规治疗组。治疗前后进行动态心电图及彩色多普勒超声心动图检测,对缺血及心功能的相关指标作对比观察。结果:治疗后ST段压低的次数及其持续时间与心肌缺血总负荷两组均有明显减少,与治疗前比较,有非常显著性差异(P<0.01),两组疗效比较,反搏组明显优于常规治疗组(P<0.01)。反搏后,左室舒张功能指标(E、A、E/A、DC、Ea、Aa、Ea/Aa、E/Ea)明显改善(P均<0.01),常规治疗组治疗前后差异无统计学意义(P>0.05)。反搏期间,患者无任何不良反应。结论:体外反搏对冠心病心肌缺血有显著疗效,且能改善左室舒张功能。Objective： It is observe the influence of enhance external counterpulsation（EECP） on left ventricular diastolic function （LVDF） in patients with coronary heart disease using ultrasound cardiogram. Methods： Seventy cases of coronary heart disease were randoml＇~＇ into EECP group （35 cases ） and routine group（35 cases）. The routine group was treated with normal treatment aspirin,isosorbide mononitrate and pavasatatin, the EECP group was treated with EECP based on the normal treatment. The changes of myocardial ischemia and cardiac function were observed by Dynamicelectrocardiogram and Doppller echocardiograpy before and after treatment. Results： Frequency and sustained time of ST stage depression,and total loading of myocardial ischemia were decreased significantly in two groups （P〈0.01 respectively） after treatment, but it decreased more significantly （P〈0.01） in EECP group than in routine group.There was no obvious difference （P〉0.05） on the left ventricular systolic fimction （CO, EF） between the two groups after treatment, the LVDF parameters（E, A, E/A, DC, Ea, Aa, Ea/Aa, E/Ea） were improved （all P〈0.01） in the EECP group, but there were not different （P〉0.05） in routine group before and after treatment. No side effects found in treating with EECP. Conclusion： There has obvious therapeutic efficacy of EECP on myocardial ischemia and LVDF in patients with coronary heart disease.

关 键 词：体外反搏 左室舒张功能 无症状心肌缺血 冠心病 多普勒超声心动图 

分 类 号：R445.1[医药卫生—影像医学与核医学]