钙磷代谢紊乱与腹膜透析的临床研究  

To Explore the Disorders of Calcium and Phosphors Metabolism in Peritoneal Dialysis Patients

作　　者：翁敏 扬荆[1] 毕丹清[1] 

机构地区：[1]昆明医学院第一附属医院肾内科,云南省昆明市650031

出　　处：《实用心脑肺血管病杂志》2009年第2期85-86,共2页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

基　　金：云南省教育厅资助项目(5Y0468C)

摘　　要：目的探讨持续性不卧床腹膜透析(CAPD)患者残肾功能和腹膜转运特性对钙磷代谢的影响。方法连续不卧床腹膜透析患者43例,透析时间3.5～34.0个月,透析剂量6～8L/d。用腹膜平衡试验测定腹膜转运功能。以残肾GRF>2ml/min为有残余肾功能的界线。结果没有残肾功能的患者血磷和钙磷乘积较有残肾功能者明显升高,差异有统计学意义(P<0.05)。结论CAPD患者普遍存在钙磷代谢紊乱,以血磷和钙磷乘积升高较明显,残存肾功能对血磷的清除起着重要的作用。Objective To investigate the irtfluence of residual renal function, and peritoneal membrane transport capacity on the calcium and phosphorus metabolism in continued ambulatory peritoneal dialysis patients （CAPD）. Methods Forty three patients undergoing CAPD from 3. 5 - 34 months with dialysis dosage 6-8L/d were researched peritoneal function characteristics are monitored using the peritoneal equilibration test （PET）. The residual renal function of the CAPD patients was set a target minimum of 2ml/min. Results The patients who had not owned residual renal function had significant elevated serum phosphorus level and value of （Ca^2＋ ） ＊ （ P2 ＋ ） （ P 〈 0. 05）. Conclusion Disorder of calcium and phosphorus metabolism, especially hyper serum phosphorus and higher calcium - phosphorus product in CAPD patients. The residual renal function plays an important role in the clearance of serum phosphorus.

关 键 词：钙磷代谢 残肾功能 腹膜转运特性 

分 类 号：R459.51[医药卫生—治疗学]