预防婴儿肺炎并发多器官衰竭的探讨  

Investigation on prevention of infant pneumonia complicated with multiple organs failure

作　　者：李炳照[1,2] 李春蕾 石海香[1,2] 任志萍 

机构地区：[1]河北省沧州市中西医结合医院 [2]河北省儿童医院

出　　处：《中西医结合实用临床急救》1998年第1期21-23,共3页

摘　　要：目的：探讨婴儿肺炎并发多器官衰竭的早期预防。方法：将１６０例无器官衰竭又无其它合并症及并发症的病情较重的患儿随机分为预防组和对照组各８０例，对照组予以常规治疗，预防组则在常规治疗基础上同时予以川芎嗪注射液、酚妥拉明、毒毛旋花子甙Ｋ治疗。结果：预防组各器官衰竭发生率明显下降，其中发生心力衰竭１４例次；氧分压（ＰａＯ２）升高７０例，降低１０例；二氧化碳分压（ＰａＣＯ２）下降６８例，升高１２例；死亡３例（３．７５％）；对照组各器官衰竭发生率明显升高（２组比较Ｐ＜０．０５和Ｐ＜０．０１），其中发生心力衰竭３６例次；ＰａＯ２升高５６例，下降２４例；ＰａＣＯ２下降５２例，升高２８例；死亡１１例（１３．７５％）。结论：对较重的婴儿肺炎早期采取预防措施可改善缺氧和二氧化碳潴留，降低多器官衰竭的发生率和病死率。Objective:To explore the prevention of infant pneumonia complicated with multiple organs failure (MOF).Methods:One hundred and sixty cases of severe infant pneumonia without organ failure and concomitant disease were divided randomly into prevention group (n=80) and control group (n=80).The control group was given conventional treatment and prevention group was given tetramethylpyrazine injection,phentolamine,strophanthinK on the basis of routine therapy.Results:In the prevention group,14 cases were complicated with heart failure,70 cases were raised and 10 cases were decreased in partial pressure of oxygen in artery (PaO2),68 cases were decreased and 12 cases were raised in partial pressure of carbon dioxide in artery (PaCO2) and 3 cases (375%) died,while in control group,36 cases were complicated with heart failure,56 cases were raised and 24 cases were decreased in PaO2,52 cases were decreased and 28 cases were raised in PaCO2 and 11 cases (1375%) died.Conclusions:Active preventive treatment to severe infant pneumonia can improve hypoxia and CO2 retention,decrease incidence of MOF and mortality.

关 键 词：肺炎 多器官衰竭 预防 并发症 婴儿 

分 类 号：R722.135[医药卫生—儿科] R725.901[医药卫生—临床医学]