粒计算在基因微阵列数据特征选择中的应用  

Application of Granular Computing in Microarray Gene Expression Data

作　　者：王俊[1] 祁云嵩[1] 韩利[1] 

机构地区：[1]江苏科技大学计算机科学与工程学院,镇江212003

出　　处：《科学技术与工程》2009年第6期1424-1427,1455,共5页Science Technology and Engineering

基　　金：国家自然科学基金(60773172)资助

摘　　要：对于许多模式识别问题来说,特征选择是一个非常重要的数据预处理技术,这对于维数高,而样本又相对较小的微阵列数据来说更是如此。提出一种将粒计算与传统的SVM-RFE算法相结合的特征选择算法。这种算法能够有效地去除大部分与分类无关的基因;并且能够搜索到基因数量相对较少而分类能力相对较强的信息基因子集。Feature selection is an important preprocessing technique for many pattern recognition problems. When the number of features is very large while the number of samples is relatively small as in the microarray data analysis, feature selection is even more important. A feature selection algorithm based on a granular computing and SVM-RFE hybrid algorithm can effectively eliminate most of the irrelevant genes, and can find a more informative gene subset in which the number of informative genes is almost least but its classification performance is almost highest.

关 键 词：微阵列基因表达数据 特征选择 粒计算 SVM-RFE算法 

分 类 号：TP301.6[自动化与计算机技术—计算机系统结构]