3T多体素^1H-磁共振波谱成像在急性脑梗死中的应用  

Application of 3T Multi-voxel^1H Magnetic Resonance Spectrum Imaging in Acute Cerebral Infarction

作　　者：袁滨[1] 艾克文[1] 袁飞[1] 陈学峰[1] 张忠强[1] 

机构地区：[1]武警医学院附属医院,天津300162

出　　处：《医疗卫生装备》2009年第3期74-76,共3页Chinese Medical Equipment Journal

摘　　要：目的:探讨3T多体素1H-磁共振波谱成像(MRS)在急性脑梗死诊断中的应用价值及各代谢产物峰值的临床意义。方法:对急性脑梗死23例患者进行常规MRI、弥散加权成像(DWI)和多体素1H-MRS成像,测量区域包括常规MRI和DWI上病灶中心区及对侧相应部位。结果:23例DWI病变区均表现为较高信号和明显高信号;病灶侧梗死灶中心区MRS均测到NAA、Cr、Cho峰值,在1.33ppm处均可见Lac双峰及与之重叠的Lip。对照区测得NAA,Cr,Cho,无Lac峰。结论:急性脑梗死区NAA峰下降,并出现Lac峰和Lip峰。选择恰当的感兴趣区及检测参数,调整测量区域的中心位置和角度,有助于波谱检查的成功。Objective To investigate the clinical value of 3T muhi-voxel ^1H-MRS technique in ACI diagnosis and the clinical significance of each metabolites peak. Methods The conventional MRI, DWI and muhi-voxel ^1H-MRS were performed by 23 ACI patients, and the conventional MRI and DWI were measured by the central area of lesion and corresponding contralateral site. Results The DWI lesion areas of 23 cases could be shown significantly higher signal and high signal, the peak of NAA, Cr, Cho were detected by MRS on the central area of focus lateral infarction, and Lac bimodal peak and overlapping Lip with it could be seen on 1.33ppm, but in contrast area no Lac peak. Conclusion In the ACI area, the NAA peak decreases, the Lac peak and Lip peak can be detected. With selecting felicitous voxel location, adjusting measurement central location and angle are conducive to the success of MRS examination. [Chinese Medical Equipment J ou rnal, 2009,30 （3） ： 74-76]

关 键 词：急性脑梗死 磁共振成像 磁共振波谱 

分 类 号：R445.2[医药卫生—影像医学与核医学] R743.33[医药卫生—诊断学]