痔疾舒洗剂质量标准研究  

Quality Standard of Zhijishu Lotion

作　　者：张新广[1] 王冬梅[1] 

机构地区：[1]广东东莞市人民医院,东莞市523018

出　　处：《中国药房》2009年第9期691-693,共3页China Pharmacy

摘　　要：目的:建立痔疾舒洗剂的质量标准。方法:采用薄层色谱(TLC)法对方中黄柏、大黄、地榆进行定性鉴别;采用高效液相色谱法测定黄柏中盐酸小檗碱的含量。结果:TLC斑点清晰、分离度好、专属性强。盐酸小檗碱的进样量在0.2375～1.9000μg范围内与峰面积积分值呈良好线性关系(r=0.9999);平均回收率为99.30%,RSD=0.03%(n=6)。结论:所建质量标准可用于痔疾舒洗剂的质量控制。OBJECTIVE： To establish the quality standard of Zhijishu lotion. METHODS： Phellodendron chinense, Radix et Rhizoma Rhei, Radix Sanguisorbae in Zhijishu lotion was qualitatively identified by TLC, and the content of berberine hydrochloride was determined by HPLC. RESULTS： The TLC spots of the constituents were clear, well - separated and specific. The linear range of berberine hydrochloride was 0.237 5-1.900 0μg（ r = 0.999 9） and the average recovery was 99.30% （RSD = 0.03%, n = 6） .CONCLUSION： The established quality standard is applicable for the quality control of Zhijishu lotion.

关 键 词：痔疾舒洗剂 质量标准 薄层色谱法 高效液相色谱法 

分 类 号：R283.61[医药卫生—中药学] R927.1[医药卫生—中医学]