针刺支沟穴与非穴激活不同脑区的功能磁共振成像比较  

An fMRI Cerebral Functional imaging Comparison On Needling in Zhigou (SJ6) vs a Sham Point

作　　者：黄泳[1] 李赣龙[1] 赖新生[2] 唐纯志[2] 杨君军[2] 

机构地区：[1]南方医科大学中医药学院,广东广州510515 [2]广州中医药大学针灸推拿学院,广东广州510405

出　　处：《成都中医药大学学报》2009年第1期3-6,共4页Journal of Chengdu University of Traditional Chinese Medicine

基　　金：国家重点基础研究发展计划(973计划)资助课题(No.2006CB504505);国家自然科学基金重大研究计划课题(No.90709027)

摘　　要：目的:运用fMRI技术观察针刺健康志愿者右侧支沟穴和非穴时不同脑区的激活情况,比较针刺支沟穴与非穴的不同。方法:16例健康志愿者,随机分为支沟穴组和非穴组,分别针刺右侧支沟穴和非穴;同时,运用GE 1.5T超导核磁共振系统完成脑部fMRI扫描,所得数据采用感兴趣区(ROI)法进行处理和分析。结果:针刺支沟穴和非穴,对双侧额叶、顶叶、颞叶、枕叶、海马、扣带回、基底节、小脑等脑区都有不同程度的激活。ROIs激活点数统计比较表明,针刺支沟穴对右侧小脑的激活大于非穴(P<0.05);激活几率和激活强度统计比较表明,针刺支沟穴与非穴对于各脑区的激活没有显著性差异(P>0.05)。结论:与"非穴"比较,针刺支沟穴对脑区的激活相对特异地指向小脑,该效应与支沟穴临床功效的中枢机制有关。Objective： To observe the cerebral activating effects of needling in Zhigou （SJ6） vs a sham point of healthy volunteers based on the technique of fMRI. Methods： Sixteen healthy volunteers were randomLy divided into SJ6 group and sham point group, and received needling in the different points on the right hand respectfully. Super nuclear magnetic resonance （ 1. ST, GE Co. ） was used to scan the brain and the obtained experimental data of the regional brain were processed and analyzed by method of Region of In- terest （ROI） . Results： The bilateral parietal, frontal, occipital and temporal lobes, basal ganglia, cingulate gyri, hippocampus and cerebellum were activated in varying degrees in both groups. The comparison of ROIs activating number showed that needling in S J6 could activate the right cerebellum specially （ P 〈 0. 05）, while the comparison of ROIs activating rate and strength showed that there was not any difference between the two groups （P 〉 0. 05） . Conclusion： Compared with that of sham point group, needling in S J6 could specially activate the cerebellum, which might be its center nerve basis for the clinical applications.

关 键 词：支沟穴 非穴 FMRI 脑功能成像 

分 类 号：R245.3[医药卫生—针灸推拿学] R741.049[医药卫生—中医临床基础]