寒冷环境骨骼肌爆炸伤组织病理学观察  

Histopathology observation of musculi skeleti explosion injury under cold environment

作　　者：张培谊[1] 邹赛英[1] 沈开金[2] 唐新萍[1] 付勇[1] 岳新华[1] 赵海华[1] 

机构地区：[1]兰州军区乌鲁木齐总医院病理科,新疆乌鲁木齐830000 [2]兰州军区乌鲁木齐总医院急诊科,新疆乌鲁木齐830000

出　　处：《现代生物医学进展》2009年第5期898-901,共4页Progress in Modern Biomedicine

摘　　要：目的:探讨高寒地区自然环境-25℃～-13℃条件下,骨骼肌爆炸伤的病理改变过程,为创-冻伤的救治提供依据。方法:对一组成年实验狗及实验羊,在室外自然寒冷环境-25℃～-13℃中,全身麻醉下用铜制雷管实施爆破伤模型;观察骨骼肌爆炸伤病理组织学改变及超微结构特征。结果:爆炸伤部位的肌组织损伤的病理改变随冷冻的时间延长而呈渐进加重发展,肌细胞超微结构线粒体随时间延长退行性改变而不断的加剧。结论:在爆炸伤基础上再度受冻,机体的各种生理功能受到明显抑制,加重感染的程度,对机体功能造成较大的影响,给治疗带来更大的困难,在高寒区对爆炸伤的早期治疗、防止冻伤具有重要意义。Objective： To approach cold environment in the region from -25℃to-13℃, pathology change process of musculi skeleti explosion injury, to provide remedy for saving trauma and cold injury. Method： To establish copper detonator blasting injury model after general anesthesia during nature outdoors cold environment in the region from -25℃to-13℃ using a group of dog and sheep for experiment to observe the pathology histology change and super microstructural characteristic ofmusculi skeleti explosion injury. Re- suits： The pathology of musculi skeleti explosion injury was changed with time extension and presented a gradually-aggravated trend. Muscle cell ultra-microstructure and mitochondrion occurred with the change of retrogression and become intensified with the time. Conclusions： Various physiologic ftmction of organism was restrained to obvious repression when adding the cold injury to the musculi skeleti explosion injury. Aggravating the degree of infection, it brought bigger influence on organism function, and more difficulties in treatment. The experiment had important significance for preventing cold injury and earlier treatment for cold injury in cold environment.

关 键 词：骨胳肌 爆炸伤 寒冷环境 

分 类 号：R826.5[医药卫生—临床医学]