感音神经性耳聋患者听觉皮层血氧依赖水平功能磁共振研究  

Functional MRI Study of Auditory Cortex in Sensorineural Hearing Loss Patients

作　　者：倪萍[1] 陈自谦[2] 毛春丽[3] 叶友强[2] 许尚文[2] 

机构地区：[1]南京军区福州总医院医学工程科,福建福州350025 [2]南京军区福州总医院医学影像科,福建福州350025 [3]南京军区福州总医院耳鼻喉科,福建福州350025

出　　处：《中国医疗设备》2009年第3期3-5,共3页China Medical Devices

基　　金：福建省自然科学基金计划资助项目(2006J0371);南京军区"十一五"计划课题(06Z49)。

摘　　要：利用BOLD-fMRI技术观察22例单侧中重度感音神经性耳聋患者纯音刺激时,感音神经性耳聋患者大脑两半球听觉皮层激活情况,对激活体积和信号强度进行定量分析,并探讨BOLD-fMRI定量分析对揭示感音神经性耳聋患者听觉皮层特点的应用价值。实验发现感音神经性聋患者纯音刺激健耳时,对侧听觉半球优势消失,其听觉皮层可能发生了结构重塑。BOLD-fMRI was used to observe the volume and intensity of the activated auditory cortex evoked by pure tone stimuli in sensorineural hearing loss patients, to analyze the volume and intensity of two hemispheres of activated auditory cortex quantitatively, and to compare the difference of auditory cortex between left and tight hemispheres. Finally, the characteristic of the auditory cortex of sensorineural hearing loss patients was discussed. When normal ears of sensorneural hearing loss patients were stimulated by pure tone, the eontralateral hemisphere predominance disappeared. These results seemed to show a plasticity of auditory cortex of monaural deaf patient.

关 键 词：磁共振 血氧水平依赖 功能磁共振成像 听觉皮层感音神经性耳聋 

分 类 号：R445.2[医药卫生—影像医学与核医学]