3D-FSPGR动态增强联合DWI诊断肝内小结节病变  

Application of 3D-FSPGR Dynamic Enhanced MRI in Combination with Diffusion Weighted Imaging in the Diagnosis of Intra-hepatic Small Nodular Lesions

作　　者：阙松林[1] 张文昌[1] 邱丹红[1] 苏友恒[1] 袁志雄[1] 陈学飞[1] 苏鸿林[1] 熊晓玲[1] 

机构地区：[1]龙岩市第二医院医学影像科CT/MRI诊断室,福建364000

出　　处：《放射学实践》2009年第3期279-282,共4页Radiologic Practice

摘　　要：目的:探讨三维快速扰相梯度回波(3D-FSPGR)序列MRI动态增强扫描和扩散加权成像(DWI)对肝内小结节病变的诊断价值。方法:对56例经US或CT检查发现肝内小结节的患者行常规MRI平扫、3D-FSPGR动态增强及DWI检查(SE-EPI技术,b值分别为0和800 s/mm2)。对比分析3D-FSPGR三期增强扫描(A组)、DWI(B组)及这2种方法联合应用(C组)在结节检出和定性诊断方面的价值。结果:在结节检出方面:A组检出61个结节,B组检出49个,C组检出72个,3组间差异有极显著性意义(χ2=27.72,P<0.01);A组与B组比较,差异无显著性意义(χ2=5.54,P>0.05);A组、B组分别与C组比较,差异均有显著性意义(χ2值分别为11.91和27.37,P<0.01)。在结节的定性诊断方面:在取得临床或病理证实的52个病例中,A组诊断正确36例(69.2%),C组为47例(90.4%),2组间差异有显著性意义(χ2=7.21,P<0.05)。结论:联合应用3D-FSPGR动态增强扫描和DWI对肝内小结节病灶的检出和诊断具有重要的临床应用价值。Objective：To study the value of 3D FSPGR dynamic enhanced MRI in combination with diffusion weighted imaging （DWI） in the diagnosis of intra-hepatic small nodular lesions. Methods： 56 cases with intra-hepatic small nodular lesions detected by Utrasonography or CT were examined by routine conventional and 3D FSPGR dynamic enhanced MRI in combination with DWI （SE/EPI technique,b value as 0 and 800s/mm^2 respectively）. The values of detection and diagnosis of intra-hepatic small nodular lesion by 3D-FSPGR tri phase enhanced MRI （group A）, DWI （group B） and 3D-FSPGR triphase enhanced MRI in combination with DWI （group C） were compared and analyzed. Results： In the respect of detecting intra-hepatic small nodular lesions,61 intra-hepatic small nodular lesions were detected by （group A）,49 lesions by （group B） and 72 lesions by （group C）,significant statistical differences were existed （χ^2 = 27.72, F〈0.01）. No statistical difference was existed between （group A） and （group B）（χ^2=5.54,P〉0.05）. As （group A） as well as （group B） compared with （group C） separately, significant statistical difference were existed （χ^2 = 11.91 and 27.37 respectively, P〈 0.01 ）. In the respect of qualitative diagnosis of intra-hepatic small nodular lesions,there were 52 clinical or pathology proved nodular lesions, correct diagnosis was obtained in 36 cases （69.2 % ） by （group A）, 47cases （90.4 % ） by （group C）, with significant statistical difference （χ^2= 7.21）. Conclusion： 3D-FSPGR dynamic enhanced MRI in combination with DWI showed important clinical value in the aspects of detecting and diagnosis of intra-hepatic small nodular lesions.

关 键 词：磁共振成像 动态增强 肝肿瘤 扩散加权成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R735.7[医药卫生—诊断学]