甘温除大热法对冠心病患者炎性因子的干预作用  

Effect of Astragalus membranaceus on the expression of C reactive protein in coronary heart disease patients

作　　者：孙萍[1] 赵莉[1] 刘艳[1] 燕芳芳[1] 刘运芳[1] 赵玉霞[1] 

机构地区：[1]山东大学齐鲁医院中医科,山东济南250012

出　　处：《中国老年学杂志》2009年第6期717-718,共2页Chinese Journal of Gerontology

基　　金：国家自然科学基金资助项目(30472262)

摘　　要：目的观察中药黄芪对不同年龄段冠心病(CHD)患者的临床疗效。方法选择42例CHD患者,根据年龄分为中青年组(35～59岁,20例)、老年组(60～77岁,22例)。2组CHD患者在常规治疗基础上加用中药黄芪,每日30g,4w为一个疗程,共治疗三个疗程,分别在治疗前后测定其血清C反应蛋白(CRP)含量。结果经黄芪治疗后,CRP水平较治疗前均有不同程度的下降(P<0.01)。其中老年组CRP水平下降更为明显,与中青年组比较差异显著(P<0.05)。结论中药黄芪能够有效地抑制CHD患者的血清CRP水平,对老年患者疗效尤其显著。Objective To observe the effect of Astragalus membranaceus （AM） on the expression of C reactive protein （CRP） in different ages patients with coronary heart disease （CHD）. Methods 42 CHD patients were divided into middle age （35 -59 years） and old age （60 - 77 years） groups. All patients were treated with AM. The level of CRP was measured before and after treatment. Results After treatment with AM, the level of serum CRP were decreased in the two groups （ P 〈 0. 01 ） , while the level of serum CRP was markedly decreased in the old age group （ P 〈 0.05 ）. Conclusions AM has the effects of inhibiting the expression of CRP, which has particular therapeutic effect on the old CHD petients.

关 键 词：冠心病 黄芪 C反应蛋白 

分 类 号：R256.2[医药卫生—中医内科学]