胰岛素泵在糖尿病围手术期临床应用研究  

clinical Study of Insulin Pump for Diabetic Patients in Perioperative Period

作　　者：张红军[1] 张绍义[1] 左致煌[1] 郑立[1] 王静[1] 赵英[1] 

机构地区：[1]广元市中心医院内分泌科,四川广元628000

出　　处：《华西医学》2009年第3期668-670,共3页West China Medical Journal

摘　　要：目的:研究糖尿病围手术期应用胰岛素泵持续皮下输注胰岛素的临床疗效。方法:68例糖尿病围手术期患者随机分为33例采用胰岛素泵持续皮下输注胰岛素治疗(CSII组),对照组35例采用常规多次皮下注射胰岛素治疗(MSII组),分别对术前、术后的相关指标进行对比研究。结果:治疗后两组各时点血糖均较治疗前显著下降(P<0.01)。CSII组达到目标血糖所用的时间明显少于MSII组(2.9比7.2天)(P<0.05),血糖达标率优于MSII组(93.9%比77.1%)(P<0.05),低血糖发生率低于MSII组(9.1%比34.3%)(P<0.01)。待手术时间(4.2比9.4天)和住院时间(16比24天)明显缩短(P<0.05),但两组住院总费用无差异(P>0.05)。结论:CSII在糖尿病患者围手术期中应用疗效及安全性方面优于MSII。Objective：To evaluate the clinical effects of continuous subcutaneous insulin injection（CSII）by using insulin pump for diabetic patients in perioperative period. Methods： Sixty-eight diabetic patients in perioperative period were divided into CSII group （ 33 patients） and multi-subcutaneous insulin injection （MSII） group （ 35 patients）. The changes of some clinical indexes were compared between the 2 groups before and after the treatment. Results：The blood glucose level of the patients in both groups decreased evidently after the therapy（P〈0.01）. The duration to achieve the target for blood glucose in CSII group [2.9d]was shorter than that in MSII group[7.2d] ,P〈0.05 ;the incidence of hypoglycemia in CSII group [9.1%] was lower than that in MSII group[34.3%], P〈0.01;the time of preoperative preparation in CSII group [4.2d] was shorter than that in MSII group [9. 4d] ,P〈0. 05 ;the length of hospitalization in CSII group [16d] was also shorter than that in MSII [24d], P〈0. 05; total expense of hospitalization in CSII group was almost as much as that in MSII,P〉0.05. Conclusion：CSII is superior to MSII at clinical effects and safety for diabetic patients in perioperative period.

关 键 词：胰岛素泵 持续皮下输注胰岛素(CSII) 多次皮下胰岛素注射(MSII) 围手术期 

分 类 号：R587.1[医药卫生—内分泌] R619[医药卫生—内科学]