妊娠期糖代谢异常并发新生儿低血糖的相关研究  

Study for Neonatal Hypoglycemia in Women with Abnormal Gestational Glucose Tolerances

作　　者：王小杰[1] 方敏[1] 徐先明[1] 万小平[1] 

机构地区：[1]上海交通大学附属第一人民医院,上海200080

出　　处：《实用妇产科杂志》2009年第3期164-166,共3页Journal of Practical Obstetrics and Gynecology

摘　　要：目的:探讨妊娠期糖代谢异常与新生儿低血糖的关系。方法:对我院2006年1月1日至2007年6月30日在我院产前检查及分娩的1221例单胎孕妇及其分娩的新生儿,按50g葡萄糖筛查(GCT)和75g葡萄糖耐量试验(OGTT)检查结果将产妇分为:血糖正常孕妇组、GCT阳性组、妊娠期糖耐量减低组(GIGT组)、妊娠期糖尿病组(GDM组),同时根据GDM组患者是否应用胰岛素分为无胰岛素治疗组(GDM-A1组)和胰岛素治疗组(GDM-A2组)。分别统计5组产妇分娩的新生儿中低血糖发生率及血糖均值之间的变化情况。结果:GDM-A2组的新生儿与血糖正常孕妇组、GCT阳性组、GIGT组、GDM-A1组相比,其新生儿低血糖发生率、血糖均值之间差异均有高度统计学意义(P<0.01)。结论:GDM-A2组孕妇虽经系统治疗,其分娩的新生儿仍应加强产后2小时血糖的监测,做到早发现、早处理新生儿低血糖。Objective： To investigate the incidence of neonatal hypoglycemia in pregnant women with abnormal gestational glucose tolerances. Methods：Glucese challenge test （50 g） and oral glucose tolerance test （75 g） were performed in 1221 pregnant women who had antenatal care and delivered in the department of obstetrics and gynecology of first affiliated people＇s hospital of Shanghai from Jan 1.2006 to Jun 30.2007. These women were divided into five groups, normal glucose level, GCT （ ＋ ）, GIGT, GDM of using insulin （GDM-A2）, and GDM of non-using insulin （GDM-A1）. Neonates with hypoglycemia of each group were counted separately. Results： There was significant difference in the incidence of neonate hypoglycemia and mean blood glucose of neonate when compared GDM- A2 with any other four groups （ P〈 0.01 ）, but there was no significant difference among normal group, GCT （ ＋ ）, GIGT, and GDM-A1 group （P〉0.05） .Conclusions：Although systematic management had been applied to these pregnant women with abnormal gestational glucose tolerances, the incidence of neonate hypoglycemia in GDM-A2 is still high. So we should take intensive care to the neonate blood glucose of GDM-A2.

关 键 词：糖尿病 妊娠 新生儿低血糖 

分 类 号：R714.256[医药卫生—妇产科学]