败血症及其死亡病例病因分析  

Causes of septicemia and death

作　　者：孔繁林[1] 储从家[1] 管新龙[1] 吴云坤[1] 

机构地区：[1]玉溪市人民医院

出　　处：《中国感染控制杂志》2009年第2期115-117,共3页Chinese Journal of Infection Control

摘　　要：目的探讨败血症及因其死亡患者的临床和细菌学特征。方法回顾性分析某院6年来临床确诊治疗的240例败血症及因其死亡的29例患者的临床和实验室资料。结果240例败血症患者血培养共分离感染菌62种，凝固酶阴性葡萄球菌（CNS）居所有病原菌首位，占27．92％；29例病死患者中，革兰阴性（G^-）杆菌（大肠埃希菌占41．38％）败血症最多，占65．52％，其次是CNS，占20．69％。死亡病例中，男性多于女性（Χ^2=5．29，P〈0．05），≥15岁者多于％15岁者（Χ^2=5．59，P〈0．05），医院感染者多于社区感染者（Χ^2=43．94，P〈0．01）。结论CNS为败血症的首要病原菌，但以大肠埃希菌为主的G杆菌仍是导致败血症患者死亡的主要病原菌。败血症死亡者中，以成人、男性、医院感染者居多。Objective To investigate the clinical and bacteriological characteristics of the death of patients with septicemia. Methods Clinical and experimental data of 240 patients with septicemia （29 patients died from septicemia） in a hospital in 6 years were analysed retrospectively. Results Sixty-two species of pathogens were isolated from 240 patients, the main pathogens were Coagulase negative Staphylococcus （CNS）, which accounting for 27. 92%; among 29 patients died from septicemia, the majority were septicemia caused by gram-negative bacilli （41.38% were Escherichia coli）, which accounting for 65. 52%, the next were CNS （20. 69%）. Among patients died from septicemia, male patients were more than female patients （Χ^2 = 5. 29, P〈0. 05）, age≥15 years old were more than age〈15 years old （Χ^2 = 5.59, P〈0. 05）, nosocomial infections were more than community-acquired infections （Χ^2 = 43. 94, P〈0. 01 ）. Conclusion CNS are the main pathogens causing septicemia, but Escherichia coli of grarrrnegative bacilli is still the main pathogen. Among patients died from septicemia, the predominant are adults, male patients and patients with nosocomial infection.

关 键 词：败血症 血流感染 脓毒症 病死 医院感染 凝固酶阴性葡萄球菌 大肠埃希菌 

分 类 号：R515.3[医药卫生—内科学]