载药纳米羟基磷灰石的研究  

Study on the drug-loaded nano-hydroxyapatite

作　　者：孙夏囡[1] 何文[1] 闫顺璞[1] 周伟家[1] 

机构地区：[1]山东轻工业学院材料科学与工程学院,山东济南250353

出　　处：《山东轻工业学院学报（自然科学版）》2009年第1期45-48,共4页Journal of Shandong Polytechnic University

基　　金：山东省教育厅项目(J07YA01)

摘　　要：载药纳米微粒常作为近年来理想的药物载体系统。纳米羟基磷灰石(HAP)是一种重要的无机生物医用材料,它具有较高的药物吸附量及良好的生物相容性,有望作为一种新的控释制剂。本文重点论述了纳米羟基磷灰石作为药物载体的独特性能及研究现状,并对药物的包载和释放进行了讨论。Drug-loaded nanoparticles are often used as ideal drug delivery systems recently. Nanoscale HAP is an important inorganic biomedical materials from various applications point of view. It has high absorbability for medicine and enhanced biocompatibility, which is perspective to be used as a new controlled release preparation. This article emphatically trends on its unique properties and relevant research. Also certain issues about the drug load and drug release are covered.

关 键 词：纳米羟基磷灰石 药物载体 生物相容性 控制释放 

分 类 号：TQ174.75[化学工程—陶瓷工业] TB383[化学工程—硅酸盐工业]