95例窒息新生儿血液阴离子间隙值与缺氧缺血性脑病的关系  

Study on the relation between AG and HIE in 95 new-born with asphyxia

作　　者：叶国华[1] 方润婷[1] 柴鸣荣[1] 邓皓辉[1] 

机构地区：[1]东莞市人民医院,广东东莞523018

出　　处：《赣南医学院学报》2009年第1期26-27,共2页JOURNAL OF GANNAN MEDICAL UNIVERSITY

摘　　要：目的:探讨窒息新生儿血液阴离子间隙(AG)与新生儿缺氧缺血性脑病(HIE)发生率间的关系,以助早期诊治。方法:采用全自动血气分析仪对95例窒息新生儿进行外周动脉血血气分析,同时进行血电解质检测,计算具体的AG值。结果:窒息新生儿存在轻到中度的酸中毒,正常AG组与高AG组之间pH值和BE值差别无显著意义(P(0.05)。但两组之间HIE的发生率差异有显著性意义(P(0.05)。结论:AG值可作为预测窒息新生儿HIE的重要指标,指导临床诊断和治疗。Objective： To study the relation between blood Anion Gap（AG） and Hypoxic-ischemic encephalopathy（HIE） in newborn babies with asphyxia, which can help to make early diagnosis and treatment. Method： Analysis of arterial blood gas by Fully Automatic Blood-Gas Analyzel （FABGA） 95 new-born babies with asphyxia, and assessing the blood electrolyte and then calculating the value of AG at the same time. Results： The new-born babies with asphyxia all have light to middle acidosis; the pH and BE has no remarkable difference between normal AG group and high AG gronp （ P 〉 0. 05 ） , while the HIE occurrent rate has remarkale difference （ P 〈 0. 05 ）. Conclusion ： AG value can be taken as one of the important index for the forecast of HIE in new-born babies with asphyx- ia, and can be used for clinic diagnosis and treatment.

关 键 词：窒息 新生 阴离子间隙 缺氧血性脑病 

分 类 号：R722.12[医药卫生—儿科]