性激素对豚鼠心肌细胞膜Na^+,K^+-ATP酶活力的影响  

The effect of Sex hormoes on Na^+,K^+-ATP ase activity in myocardial cell membrane

作　　者：赵玉珍[1] 陈晓光[1] 郭忠兴[1] 

机构地区：[1]佳木斯医学院药理教研室

出　　处：《佳木斯医学院学报》1990年第3期208-210,309-310,共3页

摘　　要：采用Matsui and Schwartz方法制备Na^+,K^+—ATP酶液,Harry法测定无机磷含量,间接测定心肌细胞膜Na^+,K^+—ATP酶活力,实验结果表明,丙酸睾丸素、已烯雌酚对心肌细胞膜Na^+,K^+—ATP酶活性均有明显的抑制作用。但丙酸睾丸素呈正相关,已烯雌酚呈负相关,说明性腺激素可以使心肌细胞膜上的Na^+,K^+—ATP酶活性降低。Na^+, K^+-ATP ase fluid was prepared by Matsui and Schwartz's methods and inorganic phosphorus, by Harry's method and Na^+, K^+ -- ATP ase activity in myocardial cell membrane, by a indirect way. The results indicated that Testosteroni Propionas and Diethylstilbestrol significantly inhibited Na^+, K^+ -- ATP ase, suggesting that sex hormones decreased Na^+, K^+ -- ATP ase activity in myocardial cell membrane.

关 键 词：性激素 心肌细胞膜 ATP酶 

分 类 号：R977.12[医药卫生—药品]