甲磺酸培氟沙星注射液稳定性及有效期预测  被引量:1

Prediction of the stability and expiry term of Pefloxacin Mesylate Citrate Injection

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作  者:王明乐[1] 刘俊芳[1] 

机构地区:[1]河南科技大学第一附属医院,河南洛阳471003

出  处:《中国当代医药》2009年第4期50-51,共2页China Modern Medicine

摘  要:目的:考察甲磺酸培氟沙星注射液的稳定性,并预测其室温贮存有效期。方法:用分光光度法测定甲磺酸培氟沙星注射液的含量;用初均速法预测其有效期。结果:本品在室温、高温条件下稳定;在光照下色泽变深,含量及pH值有较明显的变化。结论:甲磺酸培氟沙星注射液应避光贮藏。Objective: To study the stability of Pefloxaein Mesylate Injection at room temperature in order to predict its expiry term. Methods: The content of Pefloxaein Mesylate Injection was determined by speetrophotometry, the expiry term was predicted by initial average rate method. Results: Pefloxacin Mesylate Injection was stable at room or high tempera- ture. The content and pH value of Pefloxacin Mesylate Injection changed markedly and its color darkened when it was ex- posed to sunlight at room temperature. Conclusion: The Pefloxaein Mesylate Injection should be kept in a dark place.

关 键 词:甲磺酸培氟沙星注射液 有效期 初均速法 

分 类 号:R96[医药卫生—药理学]

 

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