微波辅助合成5-硝基水杨酸的研究  

Study on Synthesis of 5-Nitrosalicylic Acid under the Irradiation of Microwave

作　　者：柴多里[1] 孙晋秋[1] 周磊[1] 葛业锋[1] 

机构地区：[1]合肥工业大学化工学院,安徽合肥230009

出　　处：《化工时刊》2009年第3期4-6,共3页Chemical Industry Times

基　　金：安徽高校省级自然科学研究重点计划项目(KJ2008A066)

摘　　要：以醋酸和醋酸酐的混和液为溶剂、浓硝酸为硝化剂,在冰浴中微波辐射下一步法直接合成5-硝基水杨酸,粗产率可达88.3%。经50%乙醇重结晶得到淡黄色粉状固体,产率为82.6%,产物结构经IR,1H NMR表征并得到确认。Under the irradiation of microwave, 5 -nitrosalicylic acid was synthesized with one -step method in ice bath, using acetic acid and acetic anhydride as mixed solvent, concentrated nitric acid as nitrating agent. The crude yield was 88.3%. Light yellow powder was obtained after recrystallization from 50% ethanol, the yield was 82.6%, and the structure of the product was confirmed by IR and 1H NMR.

关 键 词：微波 水杨酸 硝化 

分 类 号：TQ245[化学工程—有机化工]