宫颈癌子宫动脉血管网三维模型的构建  

Construction of the three-dimensional model of human uterine arterial vascular network of cervical cancer

作　　者：刘萍[1] 欧阳振波[1] 陈春林[1] 黄睿[1] 李泽宇[2] 唐雷[2] 余艳红[1] 刘畅[2] 全显跃[3] 梁波[3] 黄凡衡[3] 洪辉文[2] 吴坤成[2] 钟光明[2] 胡杰威[2] 李鉴轶[2] 钟世镇[2] 

机构地区：[1]南方医科大学南方医院妇产科,广东广州510515 [2]南方医科大学临床解剖学研究所,广东广州510515 [3]南方医科大学珠江医院影像科,广东广州510282

出　　处：《中国实用妇科与产科杂志》2009年第3期202-205,共4页Chinese Journal of Practical Gynecology and Obstetrics

基　　金：国家高技术研究发展(863)计划(2006AA02Z343,2006AA01Z310);广东省科技计划(2006B60101037);广东省自然科学基金(8151051501000021)

摘　　要：目的研究宫颈癌子宫动脉血管网的解剖学形态及血供分布情况。方法2008年9月南方医科大学南方医院妇产科获取经病理证实的宫颈癌子宫、双附件及阴道标本一套,用15%的过氯乙烯填充剂经子宫动脉和卵巢动脉行分色灌注并铸型,观察宫颈癌子宫动脉血管网的解剖学形态及血供分配。结果构建宫颈癌子宫动脉血管网模型具有子宫动脉血管网的基本形态特征,可清楚显示子宫动脉各主要分支、次级分支和细小血管网结构。宫颈癌癌灶部位血供丰富,血管形态紊乱,由双侧子宫动脉下行支供应,以患侧为主,但与对侧存在丰富的交通支,供血范围超过正常宫颈范围并包括部分阴道上段及左侧宫颈旁转移病灶;子宫动脉上行支近宫颈内口处的螺旋动脉通过交通支也参加部分供血。结论应用血管铸型技术可成功构建宫颈癌子宫动脉血管网三维模型,通过模型可了解子宫动脉血管网及宫颈癌病灶的血供特点。Objective To construct the three-dimensional （3D） model of uterine arterial vascular network of cervical cancer in vitro through vascular casting to study its anatomical feature and its blood distribution. Methods Collect a set of specimen with uterus, vagina and uterine adnexa from a cervical cancer patient who also had a history of cesarean section, form the Department of Obstetrics and Gynecology in Nanfang Hospital of Southern Medical University in September 2008, infuse with 15% chlorinated poly vinyl chloride through the uterine artery and the ovarian artery, and then east. Observe the anatomical feature and the blood distribution of the uterine arterial vascular network of cervical cancer. Results The uterine arterial vascular network of cervical cancer was constructed successfully by 15% chlorinated poly vinyl chloride. It had the basic characteristics of the human uterine artery vascular network, and clearly showed the branches of the uterine artery and the vascular network. The major blood supply of the lesion came from the bilateral descending branch of the uterine artery and its supplying extent excessed the cervix and reached the vagina. The ascending branch of uterine artery also participated in some of the blood supply through the traffic branches at the internal os uteri. Besides, the blood supply of the lesion was plentiful and lesion side mainly, existing communicating branches with the opposite side. Conclusion It is an effective way of constructing the 3D model of uterine arterial vascular network of cervical caneer through vascular casting. Based on the model; the blood supply of uterine arterial vascular network and cervical lesion could be studied.

关 键 词：宫颈癌 子宫动脉 三维血管铸型 

分 类 号：R71[医药卫生—妇产科学]