72例传导性聋患者多频稳态诱发电位与纯音测听的相关性  

Correlation between multi-frequency steady-state evoked potential and pure-tone audiometry in 72 patients with conductive hearing loss

作　　者：宋江顺[1] 王心旺[2] 谢景华[1] 李鹏[1] 吴晓钟[1] 高雄辉[1] 梁勇[3] 李苏卫[3] 谭慈珍[3] 谭曼玲[3] 

机构地区：[1]广州医学院附属广州市第一人民医院耳鼻咽喉科,510180 [2]广州医学院培训学院 [3]南方医科大学南方医院耳鼻咽喉科

出　　处：《中华生物医学工程杂志》2008年第5期371-373,共3页Chinese Journal of Biomedical Engineering

基　　金：广东省自然科学基金（04009582）,志谢 感谢南方医科大学基础部卫生统计学教研室张超讲师在SPSS分析软件运用上的大力帮助.

摘　　要：目的探讨多频稳态诱发电位，即听觉稳态反应（ASSR）与纯音听阈在传导性聋患者诊断中的相关性。方法对72例传导性聋患者的72耳分别行ASSR和纯音测听测试，并进行ASSR与纯音听阈的相关性分析。结果对于传导性聋的诊断，ASSR反应阈与纯音听阈的相关性分析显示，在不同刺激声信号载波频率情况下二者的相关性：0．5kHz（r=0．634，P〉0．05）、1kHz（r=0．792，P〈0．05）、2kHz（r=0．814，P〈0．05）、4kHz（r=0．927，P〈0．01）。除低频（0．5kHz）外，随着频率增高，二者相关性越高。不同程度气骨导差传导性聋患者中，ASSR反应阈与纯音听阈的相关性：气骨导差≤30dBHL组（r=0．723，P〈0．05），气骨导差31—60dBHL组（r=0．816，P〈0．05）。结论ASSR与纯音昕阈有相关性，ASSR对传导性聋诊断有临床应用价值。Objective To explore the correlation between multi-frequency steady-state evoked potential, namely auditory steady state responses（ASSR） and pure-tone audiometry in diagnosis of conductive hearing loss. Methods Seventy-two ears of 72 patients with conductive heating loss were tested by ASSR and pure-tone audiometry respectively, then the correlation between ASSR and pure-tone audiometry was analyzed. Results For the diagnosis of conductive hearing loss, under the sound stimulations of different carrier frequency, the analysis of correlation between the thresholds of ASSR and pure-tone audiometry showed 0.5 kHz（r =0. 634, P 〉0. 05）, 1 kHz（r = 0. 792, P 〈0.05）, 2 kHz（r =0. 814, P 〈 0.05）, 4 kHz（r = 0. 927, P 〈0.01 ）. Except 0.5 kHz, the thresholds of ASSR were correlated to pure tone thresholds, and the correlationships increased with the increase of carrier frequency. The correlations between the thresholds of ASSR and pure-tone audiometry in patients with varying degrees of air-bone gap showed ≤30dB HL group（ r =0. 723 ,P 〈0. 05） , 31-60 dB HL group （r =0. 816,P 〈0.05） . Conclusion ASSR is correlated to puretone audiometry, and it would he useful in diagnosis of conductive hearing loss.

关 键 词：诱发电位 听觉 测听法 纯音 听觉丧失 传导性 听力检查 多频稳态诱 发电位 气骨导差 

分 类 号：R764[医药卫生—耳鼻咽喉科]