非男性不育卵巢低反应患者体外受精方式的临床分析  

Clinical Analysis of In Vitro Fertilization Methods in Non-male Infertility Patients with Poor Ovarian Response

作　　者：苏迎春[1] 冯双苗[1] 孙莹璞[1] 郭艺红[1] 

机构地区：[1]郑州大学第一附属医院生殖医学中心,450052

出　　处：《中国计划生育学杂志》2009年第3期166-168,共3页Chinese Journal of Family Planning

摘　　要：目的:探讨非男性不育行体外受精-胚胎移植(IVF-ET)治疗时卵巢低反应者受精方式的选择。方法:回顾性分析行IVF-ET治疗的118例非男性不育的卵巢低反应患者资料,比较行常规IVF组和卵胞浆内单精子注射(IC-SI)组间的卵冠丘复合体(OCCC)受精率、优质胚胎率、胚胎利用率、OCCC利用率、临床妊娠率和早期流产率。结果:ICSI组的OCCC利用率高于常规IVF组,差异有统计学意义(P<0.05),OCCC受精率、优质胚胎率、胚胎利用率、临床妊娠率和早期流产率两组差异无统计学意义(P>0.05)。结论:ICSI不能改善非男性不育的卵巢低反应者的受精率、胚胎质量和妊娠结局,不建议对其行ICSI受精;卵巢低反应并非ICSI的适应证。Objective： To explore the choices of in vitro fertilization -embryo transfer （IVF -ET） methods in non -male infertility patients with poor ovarian response. Methods： The data of 118 non - male infertility patients with poor ovarian response suffered IVF - ET were analyzed retrospectively. The fertility rates of oocyte - corona - cumulus complex （OCCC） , rates of high quality embryos, utilization rates of embryos, utilization rates of OCCC, clinical pregnancy rates and early abortion rates were compared between the conventional IVF group and the intraeytoplasmic sperm injection （ICSI） group. Results： The utilization rates of OCCC in the ICSI group was higher than the conventional IVF group, with significant differences （P 〈 0.05 ）, and the differences of the fertility rates of OCCC, rates of high quality embryos, utilization rates of embryos, clinical pregnancy rates and early abortion rates between the 2 groups were not statistically significant （ P 〉 0. 05 ）. Conclusion ： ICSI cant improve the fertility rate, embryo quality and the outcome of pregnancy in non - male infertility patients with poor ovarian response. So ICSI is not suggested for these patients, and poor ovarian response is not the indication for ICSI.

关 键 词：卵胞浆内单精子注射 卵巢低反应 体外受精 

分 类 号：R714.8[医药卫生—妇产科学]