吡啶衍生物研究(Ⅻ):2-(2-芳氧基吡啶-4-甲酰氧基)丙酸酯的合成及除草活性  

Studies on Pyridine Derivatives (Ⅻ):Synthesis and Herbicidal Activity of 2-(2-Aryloxypyridine-4-carbonyloxy)-propionates

作　　者：冉兆晋[1] 倪汉文[2] 段红霞[1] 李楠[1] 董燕红[1] 傅滨[1] 肖玉梅[1] 覃兆海[1] 

机构地区：[1]中国农业大学理学院 [2]中国农业大学农学与生物技术学院,北京100193

出　　处：《农药学学报》2009年第1期41-46,共6页Chinese Journal of Pesticide Science

基　　金：国家自然科学基金课题(20472112);国家"十五"科技攻关课题(2004BA308A22-1)

摘　　要：以2-氯-4-氰基吡啶和酚类化合物为原料,通过醚化、水解、酯化等反应合成了一系列2-(2-芳氧基吡啶-4-甲酰氧基)丙酸酯类化合物,其结构通过1H NMR和MS分析确证。生物活性测定结果表明,在1500g/hm2剂量下,部分目标化合物对油菜、反枝苋和马唐表现出较强的除草活性,用药15d内植物叶片逐渐失绿变黄,直至枯死,生长受到严重抑制。A novel series of 2-（2-aryloxy pyridine4-carbonyloxy）propionates were synthesized by etherification,hydrolysis and esterification starting from 2-chloroisonicotinonitrile and phenoles.All of the structures were comfirmed by ^1H NMR and MS spectra.Preliminary bioassay showed that they were effective to Brassica campestris L.,Amaranthus retroflexus L.and Digitaria sanguinalis（Linn.） Scop.at 1 500 g/hm2.In 15 days of adminstration,the grasses lost their green sucessively and the growth was seriously inhibited.

关 键 词：二芳醚 吡啶衍生物 合成 除草活性 

分 类 号：O626.32[理学—有机化学]