Correlations between recombination rate and intron distributions along chromosomes of C.elegans  

作　　者：Hong Li Guoqing Liu Xuhua Xia 

机构地区：[1]School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China [2]Department of Biology, University of Ottawa, Ottawa, Ont., Canada K1N 6N5

出　　处：《Progress in Natural Science:Materials International》2009年第4期517-522,共6页自然科学进展·国际材料（英文版）

基　　金：supported by the National Natural Science Foundation of China (Grant No.30660044);the Ph.D. Programs Foundation of Ministry of Education of China (Grant No.20050126003)

摘　　要：Generally speaking, the intron size positively correlates with recombination rate in Caenorhabditis elegans genome. Here, we analyze the correlations between recombination rate and some measures of different intron lengths so as to know whether the recombination influences the introns of different lengths in the same way. Results show that the correlation between the recombination rate and the percentage of short introns （〈 100 bp） is negative, but the correlation between the recombination rate and the percentage of introns that are larger than 500 bp is positive. Average intron length correlates positively with the recombination rate for introns whose length is in the range of 100-1000 bp. We speculate that the recombination mainly exerts impact on introns whose length ranges from 100-1000 bp. We also show that the average intron number per zene correlates negatively with the recombination rate.Generally speaking, the intron size positively correlates with recombination rate in Caenorhabditis elegans genome. Here, we analyze the correlations between recombination rate and some measures of different intron lengths so as to know whether the recombination influences the introns of different lengths in the same way. Results show that the correlation between the recombination rate and the percentage of short introns (<100 bp) is negative, but the correlation between the recombination rate and the percentage of introns that are larger than 500 bp is positive. Average intron length correlates positively with the recombination rate for introns whose length is in the range of 100-1000 bp. We speculate that the recombination mainly exerts impact on introns whose length ranges from 100-1000 bp. We also show that the average intron number per gene correlates negatively with the recombination rate.

关 键 词：Recombination rate Percentage of introns Intron length Intron number per gene C. elegans 

分 类 号：Q343.1[生物学—遗传学] Q348