胰岛素强化治疗对急性心肌梗死应激性高血糖患者的疗效观察  

Therapeutic effect of insuline intensification therapy on stress hyperglycemia in acute myocardial infarction

作　　者：哈玲梅[1] 喻丽华[1] 高恩香[1] 

机构地区：[1]武警医学院附属医院急诊科

出　　处：《武警医学》2009年第3期251-254,共4页Medical Journal of the Chinese People's Armed Police Force

摘　　要：目的分析急性心肌梗死患者病情与血糖水平的关系,观察胰岛素强化治疗对急性心肌梗死应激性高血糖患者的疗效。方法分析我院2004年1月~2007年11月间125例急性心肌梗死患者的临床资料,比较胰岛素强化治疗和常规血糖控制的临床疗效。结果低氧血症、肠功能障碍、ALT、AST、血肌酐、尿素氮、肌钙蛋白、血清白蛋白和血钙水平与血糖有相关性（P〈0.01或P〈0.05） 与对照组相比,治疗组患者住院天数明显缩短（P〈0.01） 感染、全身炎症反应、多脏器功能不全和病死率均明显降低（P〈0.01）。结论应激性高血糖可加重急性心肌梗死患者的病情,胰岛素强化治疗能提高疗效。Objective To study the relationship between＇morbid condition and blood sugar level in acute myocardial infarction, and observe the therapeutic effect of insuline intensification therapy on stress hyperglycemia in acute myocardial infarction. Meth- otis The clinical and laboratory data on the acute myocardial infarction were analyzed by multiple linear regression related to blood sugar level in acute myocardial infarction patients, and the therapeutic effects were compared between the insuline intensification therapy and conventional blood glucose control group. Results Hypoxemia, entero - functional disturbance, ALT, AST, serum creatinine, urea nitrogen, troponin, albumin and blood calcium significantly correlated with the blood sugar level （P 〈 0.05 or P 〈 0.01 ） ;compared with control group, hospital day curtaied significantly in treatment group（ P 〈 0.01 ） ;the lethality and incidence rate of infection, systemic inflammatory response syndrome ,and muhiple organ dysfunction syndrome also decreased remarkably in treatment group （P 〈 0.01 ）. Conclusions Stress hyperglycemia aggravates morbid condition in acute myocardial infarction; insuline intensification therapy can raise therapeutic effect of acute myocardial infarction.

关 键 词：急性心肌梗死 血糖水平 应激性高血糖 

分 类 号：R592[医药卫生—老年医学]