亚临床甲减与冠心病的相关性研究  

Relationship Study between Subclincal Hypothyroidism and Coronary Heart Disease

作　　者：徐涛[1] 

机构地区：[1]山东省东营市胜利石油管理局胜利医院,山东东营257055

出　　处：《中外医疗》2009年第10期1-2,共2页China & Foreign Medical Treatment

摘　　要：目的探讨亚临床甲减与冠心病的相关性。方法测定确认为亚临床甲减患者的血糖、血压、血脂、CRP、IMT等指标,与对照组数据比较。结果观察组冠心病发病率(37.8%)显著高于对照组发病率(21.0%)(P<0.01);观察组血清CRP(5.14±0.88)mg/L显著高于对照组血清CRP(2.41±0.48)mg/L(P<0.01);观察组IMT(1.34±0.31)mm显著高于对照组IMT(0.81±0.18)mm(P<0.05)。结论亚临床甲减导致的冠心病发病率升高可能是因为代谢失调后引起的血清CRP升高以及IMT升高所致。Objective To investigate the mechanism of coronary heart disease（CHD） by the relationship study between subclinical hypothyroidism（SH）and CHD. Methods We examined levels of blood glucose,blood-fat, blood pressure,C-reactive protein in seurm and intima-media thickness（IMT） of 98 patients and 138 control subjects Results Compared with control group, patients had higher level in CRP（5.14± 0.88）mg/L vs. （2.41±0.48）mg/L,（P〈0.01）,IMT（1.34± 0.31）mm vs. （0.81 ±0.18）mm,（P〈0.05）and the attack rate of CHD（37.8% vs. 21.0%, P〈0.01）.Conclusion SH was associated with CHD by raised CRP and IMT.

关 键 词：亚临床甲减 冠心病 相关性研究 

分 类 号：R541[医药卫生—心血管疾病]