绞股蓝减弱四氯化碳所致大鼠肝脏脂质过氧化作用  

INHIBITORY EFFECT OF GYNOSTEMMA PENTAPHYLLUM(GP) ON LIVER LIPID PEROXIDATION CAUSED BY CCl_4

作　　者：叶正君[1] 蒙缔亚[2] 

机构地区：[1]湖北药检高等专科学校,武汉430064 [2]湖北省农科院测试中心,武汉430064

出　　处：《工业卫生与职业病》1998年第2期74-76,共3页Industrial Health and Occupational Diseases

摘　　要：对绞股蓝（GP）减弱CCl4所致肝脏脂质过氧化作用进行了研究，实验将Wistar大鼠随机分为四组：A（对照组）；B（CCl4）；C（GP）；D（CCl4＋GP）。结果表明，CCl4组的脂质过氧化物（LPO）含量明显高于对照组，谷优甘肽过氧化物酶（GSH－Px）低于对照组，而同时给予GP的D组可减弱CCl4诱发的上述作用。提示：GP能减弱CCl4对肝脏的损害。The inhibitory effect of GP on liver lipid peroxidation caused by CCl4 was studied. Wistar ratswere randomly divided into 4 groups:A(control),B (CCl4),C(GP)and D(CCl4 +GP). The contentof lipid peroxide (LPO)increased and the activity of glutathione peroxidase (GSH-Px) decreased inCCl4 group compared with the control group- The lipid peroxidation caused by CCl4 was inhibited byadministering GP simultaneously. The results indicated that GP could decrease liver injury inducedby CCl4.

关 键 词：绞股蓝 肝 脂质过氧化 四氯化碳 

分 类 号：R285.5[医药卫生—中药学] R135.14[医药卫生—中医学]