儿童系膜增殖性肾小球肾炎临床与病理关系的研究  

THE RELATIONSHIP BETWEEN THE CLINICS AND PATHOLOGY OF MESANGIAL PROLIFERATIVE GLOMERULONEPHRITIS IN CHILDREN

作　　者：王培荣[1,2] 杨兴季[1,2] 许瑞英[1,2] 王芝[1,2] 李翠云[1,2] 魏伟 周庚寅 刘兴琪[1,2] 

机构地区：[1]山东医科大学附属医院儿科 [2]山东医科大学病理解剖学教研室

出　　处：《山东医科大学学报》1998年第1期74-76,共3页Acta Academiae Medicinae Shandong

摘　　要：３５例儿童非ＩｇＡ系膜增殖性肾小球肾炎，主要表现为肾病综合征、血尿及蛋白尿三种类型。对以肾病综合征表现的ＭｓＰＧＮ使用激素或细胞毒性药物治疗，其中轻度系膜病变不伴有局灶硬化者治疗效果及预后好；重度系膜增殖伴有明显局灶硬化、肾小球囊壁粘连、间质纤维化者治疗及预后均差，说明治疗效果及预后与病理形态改变轻重有关。Thirty five cases of child nonIgA mesangial proliferative glomerulonephritis (MsPGN)were studied.It was divided into 3 types by clinical manifestations:nephrotic syndrome,hematuria and proteinuria.When steroid or cytotoxic drugs were administrated to the patients of MsPGN with nephrotic syndrome,the therapeutic effects and prognosis in patients with slight mesangial changes but without focal sclerosis were good,but the therapeutic effects and prognosis in those with severe mesangial proliferation accompanied by obvious focal sclerosis and adhesion to glomerular cystic wall or interstitial fibrosis were poor.It is suggested that the therapeutic effect and prognosis are closely associated with the degree of the pathological changes.

关 键 词：肾小球肾炎 肾病综合征 病理学 临床 儿童 

分 类 号：R726.923.1[医药卫生—儿科]