增殖期糖尿病视网膜病变眼动脉的血流动力学特征  

Hemodynamic characteristics of ocular artery in proliferative diabetic retinopathy

作　　者：种泽龙[1] 陈松[1] 韩梅[1] 庞雅菊[1] 赵堪兴[1] 

机构地区：[1]天津医科大学眼科临床学院天津市眼科医院,天津300020

出　　处：《中国实用眼科杂志》2009年第4期362-365,共4页Chinese Journal of Practical Ophthalmology

基　　金：天津科技计划项目（编号：08ZCGYSF01700）

摘　　要：目的探讨应用彩色多普勒血流成像（CDFI）技术检测增殖期糖尿病视网膜病变（PDR）的眼动脉（OA）血流动力学特征。方法随机抽取PDR患者56例（56只眼）分为A组PDR合并视网膜脱离患者30例（30只眼），B组PDR不合并视网膜脱离患者26例（26只眼）；C组为其他缺血性眼病患者14例（14只眼），其中包括视网膜中央动脉阻塞（CRAO）7例（7只眼）、前部缺血性视神经病变（AION）7例（7只眼）；D组为正常对照组15例（30只眼）。分别记录四组CDFI的OA血流参数。结果PDR的A、B两组与其他缺血性眼病组舒张末期血流速度（EDV）之间，A、B两组与正常对照组EDV之间及阻力指数（RI）之间差异均有统计学意义（P〈0．01）；A、B两组与其他缺血性眼病组收缩期峰值血流速度（PSV）之间及RI之间，A、B两组与正常对照组PSV之间差异均无统计学意义（P〉0．05）。结论PDR患者OA的外周循环阻力增加、远端组织血流灌注不足，当OA的PSV降低时可合并同侧颈内动脉狭窄及缺血性脑血管病。Objective To discuss the hemodynamic characteristics of ocular artery（OA）in proliferative diabetic retinopathy （ PDR ）by the color doppler flow imaging （ CDFI）.Methods 56 PDR （ 56 eyes ）were selected randomly, among them group A included 30 PDR （ 30 eyes ）with retinal detachment, group B included 26 PDR （26 eyes）without retinal detachment;in group C 14 ischemic ophthalmopathy （14 eyes）included 7 CRAO （7 eyes ）and 7 AION （ 7 eyes ） ; control group included 15 normal persons （ 30 eyes ）.The hemodynamic parameters of OA in four groups were recorded.Results There was statistical difference（P 〈0.01 ）in EDV between group A, B of PDR and group of other ischemic ophthalmopathy respectively,in both EDV and RI between group respectively A, B and control group.There was no statistical difference （ P 〉0.05 ）both in PSV and RI between group A, B and other ischemic ophthalmopathy respectivaly, in PSV between group A, B and control group respectively.Conclusion Resistance of peripheral circulation increases and perfusion of distal tissue is insufficient in OA of patients with PDR which may be associated with ipsilateral internal carotid artery stenosis and ischemic cerebrovascular diseases when PSV of OA decreases.

关 键 词：增殖期糖尿病性视网膜病变 彩色多普勒血流成像 眼动脉 血流动力学 缺血性眼病 

分 类 号：R587.2[医药卫生—内分泌] R699.8[医药卫生—内科学]