水溶性止血纺织材料对血小板和血栓形成的影响  

Effect of Water Soluble Hemostatic Textile Materials on Platelet and Thrombus Formation

作　　者：田文华[1,2] 张镁[1,2] 雷学会[1,2] 王春仁 涂赞润[1,2] 奚廷斐[1,2] 

机构地区：[1]中国药品生物制品检定所 [2]北京纺织科学研究所

出　　处：《北京生物医学工程》1998年第1期39-42,共4页Beijing Biomedical Engineering

基　　金：北京市自然科学基金

摘　　要：水溶性止血纺织材料是脱脂纤维素经化学处理而成，具有生物止血活性。作者研究了该类止血材料对血小板粘附及体外血栓形成的影响。止血纺织材料在液体中形成胶体颗粒并吸附激活血小板，参与止血过程，血小板粘附率约５０％。体外血栓形成试验表明，在凝血机制发生障碍的情况下，Ｓ－９９和Ｓ－１００止血纺织材料仍能形成血栓，明显比海藻类止血材料要好。The water soluble hemostatic textile materials, which have biologically hemostatic activity, are chemically processed from delipided cellulose. In this paper, the effect of these materials on platelet and thrombus formation is studied. These hemostatic textile materials can form colloidal particles in liquids, absorb activated platelets and take part in hemostasia. The platelet adhesion rate of these materials is about 50%. The thrombus formation test outside the body showed that S 99 and S 100 hemostatic textile materials could still form thrombus under abnormal conditions of coagulation mechanism, and they are evidently better than kelp hemostatic materials.

关 键 词：水溶性 止血纺织材料 不溶性 血栓形成 

分 类 号：R318.08[医药卫生—生物医学工程] R364.15[医药卫生—基础医学]