梅州市2003-2007年流行性乙型脑炎流行病学分析  

Epidemiological Analysis of Japanese Encephalitis in Meizhou City from 2003 to 2007

作　　者：肖胜传[1] 谢坤清[1] 刘雅姬[1] 张玮[1] 曾国浩[1] 

机构地区：[1]广东省梅州市疾病预防控制中心,梅州514071

出　　处：《热带医学杂志》2009年第3期322-323,346,共3页Journal of Tropical Medicine

摘　　要：目的分析梅州市乙脑流行特征,为乙脑预防控制工作提供科学依据。方法采用描述性流行病学调查、ELISA检测方法对梅州市2003-2007年乙脑病例进行检测和分析。结果2003-2007年梅州市五华等6县(市、区)共发生乙脑流行病例93例。流行高峰为6月份。年龄最小8个月,最大13岁,以6～10岁为多见。发病地区以五华县(64例)为主,占68.82%。临床表现以高热、嗜睡、昏迷、抽搐和锥体受损为主,易诊断为"病毒脑"。乙脑特异性抗体IgM检出率为48.33%。结论梅州市乙脑流行高峰为6月份,流行季节、流行地区发生"病毒脑"时应作乙脑IgM抗体检测鉴别。对≤10周岁的儿童应急接种乙脑灭活疫苗是控制乙脑流行的有效措施,10～15d可达到效果。Objective To analyze the epidemic characteristics of japanese encephalitis （JE） in Meizhou city and to provide the scientific basis for the control and prevention of JE, Methods Descriptive epidemiology and ELISA were used to examine and analyze the occurrence of JE in Meizhou city from 2003 to 2007. Results 93 cases of JE were reported in Meizhou city. The peak of JE epidemic was in June.The age of patients was in the range of 8- month-old to 13-year-old, and most of the infected patients were 6 to 10-year-old.64 cases were noted in Wuhua county （68.82%）. High fever, drowsiness, coma, convulsions and cone damage were the major clinical symptoms. The disease was frequently misdiagnosed as other viral encephalitis. JE IgM antibody detection rate was 48.33%. Conclusion Epidemic of JE was peaked at June in Meizhou city. Patients with viral encephalitis in the epidemic areas or in the epidemic season should be tested for JE IgM antibody. Immunization of children below 10-year-old may reduce the incidence of JE.

关 键 词：流行性乙型脑炎 流行病学 分析 

分 类 号：R512.32[医药卫生—内科学]