金属卟啉配合物与气体小分子的仿生作用研究  

Bionic Interaction of Metalloporphyrins with Various Gaseous Molecules

作　　者：张建斌[1] 张鹏燕[2] 陈国华[2] 韩芳[2] 魏雄辉[1] 

机构地区：[1]北京大学化学与分子工程学院应用化学系,北京100871 [2]内蒙古工业大学化工学院,呼和浩特010051

出　　处：《化学进展》2009年第4期771-776,共6页Progress in Chemistry

基　　金：江西永丰县博源实业有限公司和北京博源恒升高科技有限公司资助

摘　　要：金属卟啉化学是现代化学中重要的分支之一。在自然界,金属卟啉(类似物)配合物构成了叶绿素、血红蛋白及细胞色素等生物大分子的核心部分,参与生物体内信使气体分子的体内传输过程。本文综述了不同的金属卟啉配合物(MP)与气体小分子(O2,COx,NOx,H2S等)的相互作用,此类作用对于气体小分子在体内的结合及运输起着重要的作用,同时为工业过程的设计及生物模拟提供了依据。随着在生物医学、能源、分析化学、合成催化、材料科学以及气体的传输和固定等方面的广泛应用,新型MP的设计合成、结构特点和性质研究将得到不断发展。Metalloporphyrin chemistry is an important branch in modern chemical field. In nature, the core structure of chlorophyll, haemachrome, cytochrome, and other biological macromolecules are made up of various metalloporphyrins （MP）. The MPs can participate in a series of important processes in the organism, especially in the transfer processes of messenger gaseous molecules. The bionic interactions of various MPs with O2, COx, NOx and H2S are summarized in this paper. The interactions are very important for the fixation and transfer processes of these gases in body, for the industrial processes, and for the bio-simulated processes. In the near future, with the rapid development in the synthesizing processes and the deeper researches of various characters of new MPs, the natural and man-made MPs will get more development in biomedicine, power sources, analytical chemistry, synthetic catalysis, and the transfer and fixation processes of gaseous molecules.

关 键 词：金属卟啉配合物 氧气 碳氧化合物 氮氧化合物 硫化氢 相互作用 

分 类 号：O626[理学—有机化学] Q811.2[理学—化学]