圆环病毒2型人工感染猪的排毒情况及体内分布规律的初步研究  

Virus Shed and Virus Distribution in Artificial Challenge Pigs with Porcine Circovirus type 2

作　　者：何逸民[1] 罗玉均[1] 冯春复[2] 阳燕 何兆祥 张桂红[1] 

机构地区：[1]华南农业大学兽医学院,广东广州510642 [2]中国农业科学院哈尔滨兽医研究所,黑龙江哈尔滨150001 [3]湖南益阳市赫山区畜牧水产局,湖南益阳413002

出　　处：《广东畜牧兽医科技》2009年第2期35-37,共3页Guangdong Journal of Animal and Veterinary Science

摘　　要：猪圆环病毒2型(PCV2)是引起断奶仔猪多系统衰竭综合症(PMWS)的重要病原,它给养猪业带来巨大的经济损失。本研究利用PCR及荧光定量PCR检测猪人工感染猪圆环病毒2型后的排毒及体内分布规律。结果表明,感染猪可以通过呼吸道和消化道进行排毒,而且病毒持续存在;PCV2病毒主要存在于病猪的淋巴结、肾脏、肺脏中,在肝脏和脾脏中也少量存在。Porcine circovirus type 2 （PCV2） is the main pathogen of post-weaning multisystemic wasting syndrome （PMWS） in swine, which caused enormous economic loss. In this study, the distribution of PCV2 in pigs aider artificial challenge was detected by the method of PCR and real-time PCR. The results showed that the sick pigs persistently shed virus by respiratory tracts and digestive tracts post infection, and the virus was mainly resided in lymph node, kidney, lung, and slightly in liver and spleen. In this research, the invasion mechanism was initial defined, and the theory for the diagnosis and treatment of PCV2 disease was provided.

关 键 词：人工感染 猪圆环病毒2型 体外排毒 体内分布 

分 类 号：S852.659.2[农业科学—基础兽医学]