1,25-二羟维生素D3与小儿呼吸系统疾病研究进展  

THE PROGRESS BETWEEN 1,25-DIHYDROXYVITAMIN D3 AND RESPIRATORY DISEASE IN CHILDREN

作　　者：马秀丽[1] 甄艳芬[2] 

机构地区：[1]内蒙古医学院,内蒙古呼和浩特010059 [2]中国人民解放军第253医院儿科

出　　处：《内蒙古医科大学学报》2010年第S4期36-40,共5页Journal of Inner Mongolia Medical University

摘　　要：1,25-二羟维生素D3除调节人体内钙磷平衡外,在呼吸系统还具有重要作用。临床研究发现,1,25-二羟维生素D3缺乏可使罹患支气管哮喘、反复呼吸道感染、肺炎、肺结核、肺癌危险性增高。其在呼吸系统疾病中的作用机制可能包括以下四方面:对免疫细胞的作用;对细胞周期的作用;对细胞凋亡的作用;对生长因子和癌基因的影响。1,25 - dihydroxyvitaminD3 plays many roles on the health of Human body.In addition to its central functions in diseases of bones、nervous system、muscle tissue and blood system,1,25 - dihydroxyvitamin D3 has important effects on respiratory disease in children.In this paper,studies about the important active form of vitamin D - 1,25 - dihydroxyvitamin D3 and respiratory disease in children are reviewed.We realize that the effects and mechanisms of 1,25 - dihydroxyvitamin D3 in respiratory disease in children,so as to offer reference for further treating respiratory disease in children.

关 键 词：1 25-二羟维生素D3 维生素D受体 呼吸系统疾病 小儿 

分 类 号：R725.6[医药卫生—儿科]