左心房容积指数及左心房内径指数对射血分数正常心力衰竭的诊断价值对比分析  

Compraison between index left atrium volume and index left atrium diameter of their diagnostic value for heart failure with preserved ejection fraction

作　　者：叶茜[1] 杨昕宇[1] 朱楠[1] 何大军[1] 

机构地区：[1]达州市第二人民医院超声科,四川省635000

出　　处：《中华临床医师杂志（电子版）》2012年第24期7998-8002,共5页Chinese Journal of Clinicians(Electronic Edition)

摘　　要：目的探讨超声心动图左心房容积指数(LAVI)及左心房内径指数(LADI)对射血分数保存心力衰竭(HFPEF)的诊断价值。方法选取2010年9月至2011年9月于达州市第二人民医院住院的心力衰竭患者70例,其中HEPEF患者35例,非HEPEF患者35例,分别比较2组患者左心室射血分数(LVEF)、LAVI、LADI、左心室质量指数(LVMI)、舒张早期血流速度(E)、舒张晚期血流速度(A)、早期二尖瓣减速时间(DT)、舒张早期运动速度(E')、舒张早期血流速度与舒张晚期血流速度比值(E/A)、舒张早期二尖瓣血流速度与舒张早期运动速度比值(E/E')等超声心动图指标,对敏感指标行Pearson相关分析及ROC曲线分析。结果以36ml/m2为临界点,LAVI与HFPEF具有良好相关性,特异性、敏感性和准确性均为84%。以2.5cm/m2为临界点,LADI与HFPEF具有相关性,敏感性为70%,特异性为65%,准确性为66%。结论 LAVI有望成为诊断HEPEF的新指标。Objective To explore the value of left atrium volume index(LAVI)and left atrium diameter index(LADI)in diagnosis of heart failure with preserved ejection fraction(HFPEF).Methods Thirty-five patients with HFPEF and 35 patients with Non-HFPEF recruited from Oct 2010 to Oct 2011 in the second people's hospital of Dazhou were enrolled in this study.A series of parameters including left ventricular ejection fraction(LVEF),LAVI,LADI,left ventricular mass index(LVMI),mitral low velocity peak at early diastole(E),mitral low velocity peak at the end of diastole(A),initial mitral low deceleration time(DT),mitral ring velocity at early diastole(E'),E/A ratio and E/E'ratio were measured and compared between two groups of patients(HFPEF and Non-HFPEF).Parameters exhibited significant variations between two groups were tested by Pearson association analysis and ROC curve analysis for their association with HFPEF.Results At the cutting edge of 36 ml/m2,a remarkable association between LAVI and HFPEF was observed.The specificity,sensitivity and accuracy of LAVI for diagnosing HFPEF were 84%.LADI showed a lesser association with HFPEF at the cutting edge of 2.5 cm/m2,for which the specificity,sensitivity and accuracy were 65%,70% and 66%,respectively.Conclusions LAVI might play a role as a potential indicator in the diagnosis of HFPEF.

关 键 词：心力衰竭 心房 心容量 心搏量 

分 类 号：R541.6[医药卫生—心血管疾病]