实时三维超声心动图在酒精性心肌病患者中的应用价值  

The value of real-time three-dimensional echocardiography in patients with alcoholic cardiomyopathy

作　　者：单国鑫[1] 礼广森[1] 王亚娟[2] 毕文君[1] 

机构地区：[1]大连医科大学附属第二医院超声科,辽宁省116027 [2]内蒙古民族大学附属医院电诊室

出　　处：《中华临床医师杂志（电子版）》2012年第24期8003-8006,共4页Chinese Journal of Clinicians(Electronic Edition)

摘　　要：目的探讨实时三维超声心动图(RT-3DE)在酒精性心肌病(ACM)患者中的应用价值。方法 ACM患者33例,正常对照组30例。应用RT-3DE测定左心室舒张末期内径(LVEDV),左心室收缩末期内径(LVESV),左心室射血分数(LVEF),左心室心肌质量(LVM),左心室质量指数(LVMI)及左心室容积-时间曲线参数Tmsv16-SD、Tmsv16-Dif、Tmsv16-SD/R-R(%)、Tmsv16-Dif/R-R(%)。将两组各参数进行统计学比较,同时与二维超声心动图(2DE)法测值进行比较。结果与正常对照组比较,ACM组LVEDV、LVESV、LVM及LVMI均显著增高,LVEF显著减低;ACM组Tmsv16-SD、Tmsv16-Dif、Tmsv16-SD/R-R(%)、Tmsv16-Dif/R-R(%)与对照组比较显著升高,差异均具有统计学意义(P<0.05)。RT-3DE法测LVMI、LVEDV、LVESV与LVEF呈负相关(r=-0.864,-0.808,-0.862;P均<0.01),2DE法测LVMI、LVEDV、LVESV与LVEF呈负相关(r=-0.635,-0.507,-0.698;P均<0.01)。结论 RT-3DE可反映酒精性心肌病患者左心室结构及功能异常和收缩不同步,为临床诊断提供参考价值。Objective To evaluate the value of real-time three-dimensional echocardiography(RT-3DE)in patients with alcoholic cardiomyopathy(ACM).Methods 33 patients with ACM(observation group)and 30 healthy adults(control group)were enrolled.Left ventricular end-diastolic volume(LVEDV),left ventricular end-systolic volume(LVESV),left ventricular ejection fraction(LVEF),left ventricular mass(LVM),left ventricular mass index(LVMI)and left ventricular capacity-time curve parameters including Tmsv16-SD,Tmsv16-Dif,Tmsv16-SD/R-R(%)and Tmsv16-Dif/R-R(%)were measured by RT-3DE and two-dimensional echocardiography(2DE).The parameters in two groups and measured by two methods were compared respectively.Results Compared with the control group,LVEDV,LVESV,LVM and LVMI measured by RT-3DE were significantly increased in ACM group(P<0.05).LVEF measured by RT-3DE was significantly decreased in ACM group(P<0.05).Tmsv16-SD,Tmsv16-Dif,Tmsv16-SD/R-R(%)and Tmsv16-Dif/R-R(%)measured by RT-3DE were significantly increased in ACM group(P<0.05).LVMI,LVEDV and LVESV measured by RT-3DE had negative correlation with LVEF measured by RT-3DE(r=-0.864,-0.808,-0.862;all P<0.01).LVMI,LVEDV and LVESV measured by 2DE also had negative correlation with LVEF measured by 2DE(r=-0.635,-0.507,-0.698;all P<0.01).Conclusions RT-3DE is able to reflect left ventricular dysfunction and asynchrony in alcoholic cardiomyopathy,and provide a reliable method for clinical diagnosis.

关 键 词：超声心动描记术 三维 心肌病 酒精性 心室功能 左 

分 类 号：R445.1[医药卫生—影像医学与核医学] R542.2[医药卫生—诊断学]