小分子鱼胶原蛋白粉对改善女性面部肤质的疗效及安全性观察  

Clinical effects and satefy of oral treatment with low-molecular fish collagen hydrolysate on female facial skin properties

作　　者：周双琳[1] 王海燕 岳丹霞[1] 李玲凤 樊昕[1] 杨蓉娅[1] 

机构地区：[1]北京军区总医院全军皮肤病诊治中心,100700 [2]北京盛美诺生物技术有限公司

出　　处：《实用皮肤病学杂志》2011年第3期143-146,共4页Journal of Practical Dermatology

摘　　要：目的观察小分子鱼胶原蛋白粉对改善女性面部肤质的有效性和安全性。方法 30名健康受试者,随机分为受试组和对照组。受试组15例,口服小分子鱼胶原蛋白粉,6g/d,共30天;对照组15例,不服用任何胶原类产品。对两组志愿者在受试前后进行问卷调查评分;用visia数字皮肤分析仪和soft5.5皮肤检测仪检测面部皮肤的皱纹、纹理、毛孔、棕色斑、紫外线色斑、红血丝、紫质、水份、油脂等指标。结果问卷调查结果显示,口服小分子鱼胶原蛋白粉有改善睡眠及增强体力的作用,受试组健康评分较口服前有明显改善(P<0.05)。受试组面部皮肤的细纹、毛孔、纹理、紫质、水份、油脂改善明显,与受试前及对照组相比,差异有统计学意义(P<0.05),受试前后志愿者无明显不良反应。结论口服小分子鱼胶原蛋白粉可一定程度地改善女性面部肤质,且无明显不良反应,具有较好的安全性和有效性。Objective To study the effects and safety of oral treatment with low-molecular fish collagen hydrolysate on female facial skin.Methods Thirty volunteers were randomly to divide into testing group and the control group.The testing group(15 cases) was given 6 g low-molecular fish collagen hydrolysate per day for 30 days,and no collagen hydrolysate was ingested by the control group(15 cases).Questionnaires,visia complexion analysis system and soft5.5 skin detection monitor were used for assessment the wrinkle,pore,evenness,porphynin moisture and sebum before and afer the experiment.Results Questiosnnaires rersults that low-molecular fish collagen hydrolysate is effective in improving sleep and enhancing physical function(P<0.05).Wrinkles,pores,evenness,porphynins,moisture and sebum have been improved signficantly(P<0.05) in the testing group,while there was no significant changes in the control group.Conclusion Low-molecular fish collagen hydrolysate can improve the female facial skin and it is safe and effectiive.

关 键 词：小分子鱼胶原蛋白 面部肤质 

分 类 号：R751[医药卫生—皮肤病学与性病学]