积雪草苷联合谷胱甘肽和维生素C治疗黄褐斑临床观察  

Observation on the Treatment of Melasma with Asiatic Pennywort,Glutathione and Vitamin C

作　　者：盛宏[1] 包寅德 

机构地区：[1]江苏省泰州市疾病预防控制中心皮肤病防治所,江苏泰州225300

出　　处：《中国医学文摘（皮肤科学）》2011年第2期69-70,共2页China Medical Abstracts(Dermatology)

摘　　要：目的观察积雪草苷联合谷胱甘肽和维生素C治疗黄褐斑的临床疗效。方法将74例患者随机分为治疗组和对照组,两组均予还原型谷胱甘肽(600mg)、维生素C(2g)静滴(隔日1次),治疗组同时加服积雪草苷片(24mg,3次/d)。两组均连续用药12周,分别于治疗第6周和第12周后观察疗效。结果治疗组治疗6周及12周后的有效率分别为66.67%和89.74%,对照组分别为42.86%和68.57%,二者差异均有统计学意义(P均<0.05),治疗过程中两组均未发现系统性不良反应。结论积雪草苷联合谷胱甘肽和维生素C治疗黄褐斑疗效好。Objective To observe the clinical effect of asiatic pennywort joint glutathione and vitamin C on melasma.Methods Seventy-four patients were randomly divided into the treatment group and the control group.Both groups were injected(q.o.d)with reduced glutathione(600 mg)and vitamin C(2 g).The treatment group was given asiatic pennywort tablets meanwhile(24 mg,t.i.d).The total course of treatment was 12 weeks,and the results were observed at the 6th week and the 12th week respectively.Results At the end of 6 weeks and 12 wceks treatment,the efficacy of the trcatment group was 66.67% and 89.74%,whereas control group was 42.86% and 68.57%,There were significant difference between two groups(all P<0.05),and no side effect was observed in the course of treatment for both groups.Conclusions Asiatic Pennywort combined with glutathione and vitamin C shows a better effect in the treatment of melasma.

关 键 词：积雪草苷 谷胱甘肽 维生素C 黄褐斑 

分 类 号：R758.4[医药卫生—皮肤病学与性病学]