体育运动中闭合性软组织损伤的中药软膏制剂初步研究——黄柏中盐酸小檗碱的提取工艺的实验研究  

Preliminary Study of Production Traditional Medicinal Ointments for Closed Soft Tissue Injury——Experimental Study of Extraction Process about Berberine Hydrochloride

作　　者：张扬[1] 

机构地区：[1]中北大学体育与艺术学院,山西太原030051

出　　处：《搏击（体育论坛）》2011年第11期87-89,共3页Sport Forum

摘　　要：文章的研究目的旨在筛选黄柏中盐酸小檗碱的提取工艺的初步研究。研究方法:以冷浸、温浸、回流、超声为主要提取方法,采用高效液相色谱法测定指标成分含量、酸性染料比色法测定总生物碱含量。研究结果:文章得到黄柏的最佳提取工艺为:10倍量盐酸-70%乙醇(1:100),70℃温浸180min。研究结论:通过系统的实验研究,确定了黄柏中盐酸小檗碱的提取工艺,为治疗闭合性软组织损伤软膏剂的进一步研究提供了物质基础。Objective:does the production of traditional medicine ointments for closed soft tissue injury. Methods:by the main methods of extracting Soaking Ultrasonic,using HPLC determine the content of the active ingredients,acid dye to determine the total alkali content and the drug power content. By berberine hydrochloride clinical need and smear feeling based material fusion with drug for the indicators choose based material. Results:The optimum extracting condition is:Cortex Phellodendri:adding ten times amount of Hydrochloride-70% alcohol(1:100) and refluxing and extracting for 180 min. Conclusions:determined extraction forming process of berberine hydrochloride by system experimental study for the production of traditional medicinal ointments for closed soft tissue injury and offer a material basis for further research.

关 键 词：闭合性软组织损伤 黄柏 盐酸小檗碱 提取工艺 HPLC 

分 类 号：R873[医药卫生—运动医学] R284.1[医药卫生—临床医学]