病毒性肝炎患者血浆及肝组织中心钠素  

A Study of Plasma and Liver anp Levels in Patients with Various Viral Hepati-Tides

作　　者：贺仆[1] 林浩杰[2] 

机构地区：[1]山东省千佛山医院,济南250014 [2]山东省血液中心济南血站,济南250001

出　　处：《医学检验与临床》2007年第6期22-23,34,共3页Medical Laboratory Science and Clinics

摘　　要：用放射免疫法检测了正常人和肝炎患者血浆心钠素(ANP)。结果表明ANP几何均值在重型肝炎>慢活肝>急黄肝;动态观察表明ANP均值在黄疸上升期>黄疸下降期>恢复期,均有显著差异。在重型肝炎的腹水组与无腹水组、存活组与死亡组,ANP也有显著差异,实验提示ANP代谢紊乱可能是机体水钠失调的标志之一。我们还测定了肝组织中ANP,初步认为肝组织内ANP随病情不同而含量亦有差异。The plasma levels of ANP were measured in normal individuals and patients with various viral hepatitis.The results showed that plasma level of ANP in patients with fulminant hepatitis was the highest,the secondhighwas that of chronic active hepatitis and the level of ANP in patients with acute icterohepatitis was thelowest.The level of ANP during jaundice increase period was the highest,the second high was during jaun-dice decrease period and the third was in convalescence.A significant difference of ANP level was demonstrated between ascite group and ascite-free group and between survival group and group died of fulminant hepatitis.Our results suggest that the metabolic disorder of ANP seems to be one of the marks of modulating imbalance from water and salt,ANP in liver tissue was also measured.The preliminary conclusion is that the ANP con-centrations in the liver tissue are different in patients with different clinical conditions.

关 键 词：病毒性肝炎 血浆心钠素 放射免疫法 

分 类 号：R512.6[医药卫生—内科学]