我国不同肝炎患者及献血员中SENV-D/H感染流行病学调查  

Prevalence of SEN Virus D and H Subtype lnfection in Different Type Of Hepatitis and Blood Donors

作　　者：宋玉和[1] 

机构地区：[1]山东省血液中心济南济南血站,济南20001

出　　处：《医学检验与临床》2007年第3期15-17,共3页Medical Laboratory Science and Clinics

摘　　要：目的了解SEN病毒(SENV)D亚型和H亚型在我国不同肝炎患者和献血员中的感染情况。方法采用巢式聚合酶链反应对收集的270例健康献血者和484例各型肝炎患者(包括甲肝、乙肝、丙肝和甲非戊型肝炎患者)进行SENV-D亚型和H亚型DNA检测。结果无偿献血者中SENV-D的感染率为25.9%,SENV-H为24.4%;急性甲肝患者中SENV-D的感染率为14.5%,SENV-H为32.7%;慢性乙肝患者中SENV-D的感染率炎46%,SENV-H为45.2%;在丙肝患者中SENV-D和SENV-H感染率均为65%,在非甲-非戊型肝炎患者中SENV-D的感染率为51.2%,SENV-H为43,9%。结论SENV可能为HCV和HBV具有一样的传播方式,但并不是肝病发生的原因。Objective To investigate the prevalence of SENV-D/H in different type of hepatitis and blood donors.Methods The SENVD/H subtype DNA were detected in 754 different hepatitis and blood donors in china by nested PCR.Resulls The SENV-D/H positive rate in healthy donors were 25.9% and 24.4%,from which 14.5% and 32.7% acute hepatitis A patients,46% and 45.2% in chronic hepatitis B patients,65% in hepatitis C patients,51.2% and 43.9% hepatitis non A-E patients.Conclusion SENV probably has the same ways of spreading as HCV and HBV,but is not responsible for hepatitis.

关 键 词：SENV-D亚型 SENV-H亚型 流行病学 巢式聚合酶链反应 

分 类 号：R512.6[医药卫生—内科学] R181.3[医药卫生—临床医学]