经颅多普勒超声在早期诊断老年2型糖尿病患者脑血管损害中的作用  

Tanscraniai doppler ultrasonography examination in diagnosis of the early cerebrovascular diseases in aged dia- betic patients.

作　　者：谢静芳[1] 黄雪芬[1] 郭智君[1] 

机构地区：[1]广东省人民医院老年病研究所,广东广州510080

出　　处：《中国实用内科杂志》2007年第S1期216-217,共2页Chinese Journal of Practical Internal Medicine

基　　金：2006年度省中医药局课题(1060030)

摘　　要：目的评估经颅多普勒超声(TCD)检查在早期诊断老年2型糖尿病患者脑血管损害中的作用。方法 179例老年2型糖尿病患者按眼底视网膜病变程度分糖尿病视网膜无病变(NDR)组、单纯性视网膜病变(BDR)组和增生性视网膜病变(PDR)组,并以40例老年健康者作为对照组。所有观察对象分别行 TCD 及视网膜检查,并行数据分析。结果 (1)2型糖尿病患者大脑中动脉(MCA)、大脑前动脉(ACA)、颈内动脉虹吸部(ICA)和基底动脉(BA)的收缩期峰流速(Vp)较对照组明显增高(P<0.05)。(2)PDR 组 MCA、ACA、ICA 及 BA的 Vp 值较 BDR、NDR 组和对照组明显增高(P<0.05),BDR 组较 NDR 组和对照组明显增高(P<0.05)。NDR组与对照组比较,仅 MCA 和 ACA 的 Vp 值较对照组明显升高(P<0.05)。结论老年2型糖尿病患者脑血管损害与视网膜病变程度密切相关,TCD 检查 MCA 和 ACA 的收缩峰血流速度可作为老年2型糖尿病患者脑血管损害的早期诊断指标之一。Objective To evaluate the role of TCD examination in diagnosis of the early cerebrovascular diseases in aged diabetic patients.Methods 179 cases of aged type Ⅱ diabetic patients were divided into three groups(PDR,BDR and NDB)according to their retinopathy.TCD and retina examination were performed in all patients and the data be analysed. Results (1)The systolic peak flow velocity(Vp) of MCA、ACA、ICA and BA were significant increased in diabetic pa- tients than in normal control group(P<0.05).(2) The Vp of MCA,ACA,ICA and BA were significant increased in PDR and BDR groups than in NDR and normal control groups (P<0.05).The Vp of MCA、ACA were notable increased in NDR when compare with normal control(P<0.05).Conclusion TCD examination can be used as one of the early diag- nostic methods for cerebrovascular diseases in aged diabetic patients.

关 键 词：经颅多普勒超声 2型糖尿病 老年 视网膜病变 

分 类 号：R587.1[医药卫生—内分泌] R743.3[医药卫生—内科学] R445.1[医药卫生—临床医学]