慢性病贫血与慢性系统疾病性贫血患者平均红细胞体积、红细胞分布宽度的比较  

Comparison of MCV and RDW in Patients with Anemia of Chronic Disease or Anemia of Chronic Systematic Disease

作　　者：吕霞飞[1] 吴茅[2] 

机构地区：[1]浙江医学高等专科学校,浙江杭州310053 [2]浙江省人民医院,浙江杭州310014

出　　处：《浙江医学教育》2004年第1期51-52,18,共3页Zhejiang Medical Education

摘　　要：目的:探讨平均红细胞体积(MCV)和红细胞分布宽度(RDW)检测在慢性病贫血、不同类型慢性系统疾病性贫血临床诊断的价值。方法:用Coulter STKS血细胞分析仪测定36例慢性病贫血和130例慢性系统疾病性贫血患者(肝性贫血40例、肾性贫血40例、糖尿病贫血50例)的MCV和RDW,比较不同患者MCV和RDW的差异。同时设置40例健康者作为正常对照。结果:与正常对照比较,慢性病贫血与慢性系统疾病性贫血患者的MCV值均无显著差异(P>0.05),RDW均明显升高(P<0.05);肝性慢性系统疾病性贫血患者的MCV和RDW均显著升高(P<0.01),肾性贫血患者的MCV无显著差异(P>0.05),但RDW值升高(P<0.05),糖尿病性贫血患者的MCV和RDW则均无显著差异(P>0.05)。结论:RDW可作为辅助诊断慢性病贫血和慢性系统疾病性贫血的实验室指标,MCV在临床上鉴别肝性慢性系统疾病性贫血有一定参考价值。[Objective]To determine the values of MCV and RDW examinations for clinical diagnosis in anemia of chronic disease anemia and different types of anemia of chronic systematic disease.[Method]By using Coulter STKS Blood Cell Analyzer, the values of MCV and RDW in 40 patients with anemia of chronic disease,130 patients with anemia of chronic systematic disease(40 cases of liver,40 cases of renal and 50 cases of glycosuric anemia) and 40 healthy individuals as normal control were measured.The differences of MCV and RDW values among the different patients and healthy individuals were compared. [Result]In comparison with the healthy individuals,the MCV values of the patients with anemia of chronic disease and the patients with anemia of chronic systematic disease were similar(P > 0.05) but RDW values were significantly increased(P < 0.05).The MCV and RDW values in liver anemia patients were obviously higher(P < 0.01) than that in the normal control. Only RDW value elevation for renal anemia patients(P < 0.05) and no elevated MCV and RDW values for glycosuric anemia patients(P > 0.05) could be found compared to normal control.[Conclusion]RDW could be used as a laboratory index for accessory diagnosis of anemia of chronic disease and anemia of chronic systematic disease.MCV examination had a certain reference value for clinical differential diagnosis of liver anemia.

关 键 词：慢性病贫血 慢性系统疾病性贫血 平均红细胞体积 红细胞分布宽度 

分 类 号：R556[医药卫生—血液循环系统疾病]