Biosynthesis of Polyhydroxyalkanoates  

作　　者：陈国强 吴琼 陈金春 

出　　处：《Tsinghua Science and Technology》2001年第3期193-199,共7页清华大学学报（自然科学版（英文版）

基　　金：the Major Research Project of the Ninth-Five Plan(1996 2 0 0 0 ) of China(No.96 - C0 3- 0 3- 0 2 ) ;Tsinghua U niversity"985" Project

摘　　要：Many bacteria are able to synthesize polyhydroxyalkanoates, abbreviated as PHA, as carbon and energy storage compounds. PHA with over 90 different monomer structures has been reported and the number keeps increasing. The piezoelectricity, non linear optical activity, biocompatibility and biodegradability of PHA have offered promising applications in areas such as tissue engineering, drug delivery, smart materials and degradable packaging. Various microorganisms obtained from nature, genetic engineering and mutations have been used for microbial production of PHA as biodegradable plastics. In fact, PHA synthesizing bacteria can be easily found in various locations, especially oil contaminated soils. Many bacterial strains possessing the ability to synthesize PHA with various monomers have been isolated from oil contaminated soils. In molasses contaminated soil, 40% of the isolated bacteria were capable of growing rapidly and synthesizing PHA at the same time. It seems that nature has provided endless numbers of novel PHA synthesizing strains. Many bacteria are able to synthesize polyhydroxyalkanoates, abbreviated as PHA, as carbon and energy storage compounds. PHA with over 90 different monomer structures has been reported and the number keeps increasing. The piezoelectricity, non linear optical activity, biocompatibility and biodegradability of PHA have offered promising applications in areas such as tissue engineering, drug delivery, smart materials and degradable packaging. Various microorganisms obtained from nature, genetic engineering and mutations have been used for microbial production of PHA as biodegradable plastics. In fact, PHA synthesizing bacteria can be easily found in various locations, especially oil contaminated soils. Many bacterial strains possessing the ability to synthesize PHA with various monomers have been isolated from oil contaminated soils. In molasses contaminated soil, 40% of the isolated bacteria were capable of growing rapidly and synthesizing PHA at the same time. It seems that nature has provided endless numbers of novel PHA synthesizing strains.

关 键 词：POLYHYDROXYBUTYRATE PHB polyhydroxyalkanoates (PHA) BIOPOLYMER POLYESTER 

分 类 号：Q819[生物学—生物工程]