An improved coupling reaction for the preparation of pyridylethynyl benzonitrile compounds  

An improved coupling reaction for the preparation of pyridylethynyl benzonitrile compounds

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作  者:WANG Zhiyong LIN Wenbin JIANG Chao GUO Qingxiang 

机构地区:[1]Department of Chemistry,University of Science&Technology of China,Hefei 230026,China [2]Deparment of Chemistry,Brandeis University,Waltham,MA02454,USA

出  处:《Chinese Science Bulletin》2001年第19期1606-1608,共3页

基  金:This work was supported by the National Natural Science Foundation of China (Grant No. 50073021)

摘  要:An improved coupling reaction between aromatic ring and acetylene triple bond catalyzed by palladium (0) catalyses for the preparation of pyridylethynyl benzoni-trile compounds is described. Efforts were made to improve the reaction by changing different reaction conditions and it was found that the solvent is one important factor in this situation.An improved coupling reaction between aromatic ring and acetylene triple bond catalyzed by palladium (0) catalyses for the preparation of pyridylethynyl benzonitrile compounds is described. Efforts were made to improve the reaction by changing different reaction conditions and it was found that the solvent is one important factor in this situation.

关 键 词:coupling reaction pyridylethynyl BENZONITRILES PALLADIUM catalysis. 

分 类 号:O625[理学—有机化学]

 

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