不同活化剂对稳定态二氧化氯消毒效果的比较研究  

Comparison of different acidic activator in the efficacy of disinfection of stable chlorine dioxide

作　　者：张玮[1] 侯秀丽[1] 王淑凤[1] 

机构地区：[1]山东省卫生防疫站,山东济南250014

出　　处：《中华疾病控制杂志》1999年第1期39-41,共3页Chinese Journal of Disease Control & Prevention

摘　　要：目的比较盐酸和柠檬酸作为活化剂对稳定态二氧化氯的消毒效果。方法以盐酸和柠 檬酸作活化剂，评价稳定态二氧化氯的消毒效果。结果当消毒剂为４．５ｍｇ·Ｌ－１时，消毒２ｍｉｎ， 对大肠杆菌的杀灭率分别为９９． ９９％及７８． ００％，对金黄色葡萄球菌的杀灭率分别为９９． ９９％及 ９６． ２５％。当消毒剂为９０ｍｇ·Ｌ－１时，１５ ｍｉｎ对细菌芽孢的杀灭率分别为９９．９９％及９７．００％。加 １０％小牛血清的菌悬液要达消毒效果，用盐酸活化只需１８０ ｍｇ·Ｌ－１作用５ｍｉｎ，而柠檬酸则需 ２７０ ｍｇ·Ｌ－１作用１５ ｍｉｎ。以盐酸为活化剂，二氧化氯２００ ｍｇ·Ｌ－１，５ ｍｉｎ即可灭活ＨＢｓＡｇ；而柠檬酸则需４００ ｍｇ·Ｌ－１。结论作为稳定态二氧化氯的活化剂，盐酸明显地优于柠檬酸。Objective To study which one has a better disinfecting effect on stable chlorine dioxide with hydrochloric-acid or citric-acid as activator. Methods Disinfecting effect was tested with the routine method in accordance with experiment disinfectant. Results The results showed that the efficacy of hydrochloric-acid as an activator excelled that of citric-acid as an activator. The outcomes demonstrated that the stable chlorine dioxide was activated by hydrochloric-acid and cit- ric-acid respectively, the disinfectant containing 4. 5 mg . L-1 available chlorine dioxide could kill 99. 99 % and 78. 00 % Escheritia. coli in 2 min contact time separately and the efficiency for staphylococcus. Aurreus were 99. 99 % and 96. 25 % respectively, the disinfectant solution con- taining 90 mg . L-1 available chlorine dioxide with 15 min contact time could kill 99. 99 % and 97. 00 % bacterial spores respectively when the suspension of the bacterial spores was mixed 10 % calf serum and designed to reach the efficacy of disinfection only to need 15 min with 180 mg . L-1 chlorine dioxide which was activated by hydrochloricacid, but with citric-acid would require 270 mg . L-1 in 15 min. When the stable chlorine dioxide was activated by hydrochloric-acid then the solution will contain 200 mg . L-1 available chlorine dioxide , which can lead to negative conversion for antigenicity of purified, HBsAg within 5 min by SPRLA method. If activated by citric-acid, would demand 400 mg . L-1 available chlorine dioxide. Conclusion As activators of stable chlorine dioxide , hydrochloric-acid was obviously better than citric-acid.

关 键 词：稳定态二氧化氯 活化剂 盐酸 柠檬酸 

分 类 号：R187.1[医药卫生—流行病学]