滋养细胞肿瘤糖原PAS整块显色及图像定量分析  

IMAGE ANALYSIS OF GLYCOGEN OF TROPHOBLASTIC TUMOR STAINED WITH MASSIVE PAS TECHNIQUE

作　　者：黄秀琴[1] 蒋淑萱[1] 赵如华[1] 马丽梅[1] 徐琳[1] 王继芳[1] 李坪[1] 

机构地区：[1]昆明医学院组织胚胎学教研室

出　　处：《中国组织化学与细胞化学杂志》1999年第1期105-107,共3页Chinese Journal of Histochemistry and Cytochemistry

摘　　要：应用图像分析仪，对经过ＰＡＳ整块染色的４４例滋养细胞肿瘤标本进行糖原定量测定和分析。结果表明：滋养细胞肿瘤细胞的糖原含量和细胞增生程度成正比。恶性葡萄胎（ＨＭ）（未化疗）和绒毛膜癌（未化疗）的糖原含量明显高于良性葡萄胎和正常绒毛，有极显著性差异（Ｐ＜０．０１）。恶性葡萄胎和绒毛膜癌经化疗后，糖原含量明显降低。结果提示：滋养细胞肿瘤糖原含量的图像分析，在该肿瘤的诊断、预测预后，指导临床治疗方面。Glycogen contents of 44 samples of trophoblastic tumors were detected with PAS massive staining and analyzed with image analyzer. The results showed that the ratio between glycogen content and hyperplastic degree of trophoblastic tumor was directly proportional. The glycogen contents of malignant mole and carcinoma villosum before chemotherapy were markedly higher than those of hydatidiform mole and normal villosity and significant differences (P<0 01) were found between them. The glycogen contents of malignant mole and carcinoma villosum after chemotherapy were obviously reduced. Thus detection and image analysis of glycogen content of trophoblastic tumor may provide important information for predicting the prognosis of the tumor and serving as a guide to clinical treatment

关 键 词：滋养细胞肿瘤 糖原 图像分析 人 

分 类 号：R329.24[医药卫生—人体解剖和组织胚胎学]