高频喷射通气治疗海水淹溺肺水肿时兔肺钙离子超微结构变化  

CHANGES OF ULTRASTRUCTURAL LOCALIZATION OF CALCIUM IONS IN RABBIT PE SWD LUNGS CURED BY HEJV

作　　者：李侠[1] 凌斌勋[1] 王琰[1] 张敏华[1] 赵增荣[1] 董文度[1] 徐根兴[1] 刘虹[1] 袁驾南[1] 

机构地区：[1]南京军医学院细胞生物学研究室,南京210099

出　　处：《中国组织化学与细胞化学杂志》1999年第4期399-402,共4页Chinese Journal of Histochemistry and Cytochemistry

摘　　要：用海水灌注的方法诱导海水淹溺肺水肿（ＰＥ－ＳＷＤ）， 采用高频喷射通气（ＨＦＪＶ） 治疗， 应用血气酸碱分析仪对兔动脉血气酸碱三项指标进行自动检测， 并采用Ｃａ２＋ 超微结构方法观察肺内Ｃａ２＋ 变化。结果表明肺细胞内Ｃａ２＋ 超负荷与ＰＥ－ＳＷＤ发生有关， ＨＦＪＶ 对改善ＰＥ－ＳＷＤ症状有明显作用， 同时， 细胞内Ｃａ２＋Pulmonary edema of sea water drowning (PE SWD) was induced by sea water irrigation and cured by high frequency jet venilation (HFJV). Index changes about artery blood gas and acidbase of rabbit were detected and the reaction products of Ca 2+ in the pulmonary cells were ultrastructurally observed. The results showed that the Ca 2+ inflow in pulmonary cells was related with development of PE SWD. HFJV obviously improved PE SWD symptom and reduced the Ca 2+ inflow of pulmonary cells.\;

关 键 词：海水淹溺肺水肿 高频喷射通气 血气酸碱分析 钙离子 

分 类 号：R563[医药卫生—呼吸系统]