抗解浸膏抗菌、抗病毒作用的观察  

The observe of anti-bacterium and anti-virus effect of Kan Jie extract

作　　者：包旭[1] 包定元[2] 李建农[3] 杨艳[4] 叶利民[1] 

机构地区：[1]华西医科大学药学院,成都610044 [2]华西医科大学化疗药理研究室,成都610044 [3]中国医学科学院医药生物技术研究所,北京100050 [4]泸州医学院心肌电研究室,泸州646000

出　　处：《四川生理科学杂志》1999年第1期23-25,共3页Sichuan Journal of Physiological Sciences

摘　　要：体外抗菌试验表明,抗解浸膏对金黄色葡萄球菌、表皮葡萄球菌、肺炎链球菌、甲及乙型溶血链球菌等革兰氏阳性细菌的MIC为1.56～56.0mg(生药)/ml,对大肠杆菌、克氏肺炎杆菌、变形杆菌、痢疾杆菌和嗜血流感杆菌的MIC_(50)为3.12～50.0mg(生药)/ml,对绿脓杆菌、产气杆菌的抑菌活性较低,MIG_(50)和MIC_(90)分别为50.0～200.0mg(生药)/ml,抗解浸膏还有一定的杀菌作用,MBC多数是MIC的2～4倍。抗解浸膏1:40的浓度对流感病毒A_3型在体外具有明显的抑制作用。The experiment in vitro showed that the MIC of Kan Jie extract for Staphylococcus aureus, Staphylococcus cpidermidis, Streptococcus pneumoniae was 1. 56～50. Omg( crude drug) /ml, the MIC50 for Bacillus coli, Klebsiella pneumoniae、proteus、Bacillus dysenteriae and Haemophilus in-fluenzae was 3.12～50. Omg(crude drug)/ml, the MIC50 and MIC90 for Pseudomonas aeruginosia, Bacteria gas-producing was 50.0～200. Omg(crude drug)/ml. The Kan Jie extract could kill the bacterium, the MBC was 2～4 times of MIC. The Kan Jie extract of 1:40 concentration could in hibite influenzae virus A3, in vitro.

关 键 词：抗解浸膏 抗菌作用 抗病毒作用 

分 类 号：R285.5[医药卫生—中药学]